Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles 1975-Oct
[Anti-inflammatory effect of hydroxy-9-ellipticine].
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The anti-inflammatory activity of 9-hydroxy-ellipticine is studied through various experimental models. It is particularly interesting in the guinea-pig cutaneous erythema, in the carragenin-induced oedema and in the adjuvant-induced polyarthritis in the rat. It appears in immune or non-immune induced inflammatory responses. Its important thymolytic activity can be related to its immunosuppressive effect.
