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acridone/preobčutljivost
Povezava se shrani v odložišče
3 rezultatov
Potential anti-allergic acridone alkaloids from the roots of Atalantia monophylla.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Acridone alkaloids, cycloatalaphylline-A (1), N-methylcyclo-atalaphylline-A (2) and N-methylbuxifoliadine-E (3), were isolated from the dichloromethane and acetone extracts of the root of Atalantia monophylla along with eight known acridone alkaloids: buxifoliadine-A (4), buxifoliadine-E (5),
ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of fcepsilon receptor I-mediated activation of Syk.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Engagement of the mast cell high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, induces tyrosine phosphorylation of Syk, a non-receptor tyrosine kinase, that has been demonstrated as critical for degranulation. Herein we describe a synthetic compound, ER-27319, as a potent and selective
Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Carbamazepine is an anticonvulsant which is associated with a significant incidence of hypersensitivity reactions including agranulocytosis. We have postulated that many drug hypersensitivity reactions, especially agranulocytosis and lupus, are due to reactive metabolites generated by the
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