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aglaia edulis/phosphatase
Povezava se shrani v odložišče
3 rezultatov
Aglaiabbrevins A-D, New Prenylated Bibenzyls from the Leaves of Aglaia abbreviata with Potent PTP1B Inhibitory Activity.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Four new prenylated bibenzyls, named aglaiabbrevins A-D (2, 4-6), were isolated from the leaves of Aglaia abbreviata, along with two known related analogues, 3,5-dihydroxy-2-[3,7-dimethyl-2(E),6-octadienyl]bibenzyl (7) and 3,5-dihydroxy-2-(3-methyl-2-butenyl)bibenzyl (8). The structures of the new
Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Rocaglaol is a cytotoxic cyclopenta[b]benzofuran isolated from the bark of Aglaia crassinervia. It exhibited in vitro cytotoxic activity against Lu1, LNCaP and MCF-7 cells with ED50 values of 13.8, 23.0 and 9.2 nM, respectively. DAPI staining indicated that LNCaP cells treated with rocaglaol
Silvestrol regulates G2/M checkpoint genes independent of p53 activity.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
As previously reported, silvestrol, a rocaglate derivative isolated from Aglaia foveolata, has similar potency to paclitaxel and camptothecin against cultured human cancer cells. Furthermore, silvestrol can inhibit cancer cell growth in mice without noticeable toxicity when administered up to 5
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