chondoritin sulphate 2% ( Uracyst) for bladder instillation. One bladeer instillation per week during 6 weeks.

DMSO 50% in saline for bladder instillation. One bladder instillation per week during 6 weeks

Painful Bladder Syndrome

Interstitial Cystitis

bladder instillations with either solution (DMSO or Uracyst)

Bladder instillations

Urology, University Hospitals KU Leuven

Prospective Trial Comparing Intravesical Chondroitin Sulphate 2% and DMSO in the Treatment of PBS/Interstitial Cystitis

Prospective Randomised Trial Comparing Intravesical Chondroitin Sulphate 2% and DMSO in the Treatment of Painful Bladder Syndrome/ Interstitial Cystitis

Primary endpoint: Global response assessment scale.
This is a 7 point scale asking: As compared to when you started the current study, how would you rate your overall bladder symptoms now? Seven response options are given to the patient: Markedly worse, moderately worse, slightly worse, no change, slightly improved, moderately improved, markedly improved.

Frequency measured as the mean frequency on a 3 day micturition diary
Nocturia episodes as the mean number of nocturia episodes on a 3 day micturition diary
Functional bladder capacity measured as the mean bladder capacity measured on a 3 day micturition diary
VAS pain scale
O'Leary -Sant scale

Nocturia measured on 3 day micturition diary

bladder capacity measured on 3 day micturition diary

patients refusing further treatment because of intolerance to the intravesical treatment of by lack of improvement

allium stipitatum/antidepresiv

Prospective Trial Comparing Intravesical Chondroitin Sulphate 2% and DMSO in the Treatment of PBS/Interstitial Cystitis

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