antipsychotics/edema

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[Effect of several neuroleptic, adreno-, sympatho- and cholinolytic substances on the development of experimental cerebral edema induced by nicotine].

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Prijava / prijava

The influence of some neuroleptic, adreno, sympatho- and cholinolytic substances on the development of experimental brain edema induced with nicotine was studied in tests conducted on rats. It was ascertained that marked antiedemic properties display drugs blocking the alpha-adrenoreceptors

[The effect of neuroleptics on blood proteins during development of toxic cerebral edema-brain swelling].

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Prijava / prijava

Simulation of toxic brain edema-swelling allowed one to analyze the dynamics of blood protein alteration in presence of various neuroleptics. Alterations in blood protein fractions correlated with dynamics of nervous tissue impairments. All the drugs studied exhibited similar antiswelling action

Neuroleptic malignant syndrome presenting as pulmonary edema and severe bronchorrhea.

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Prijava / prijava

Neuroleptic malignant syndrome is a rare (incidence, 0.02%-3.2%) but dangerous complication following the use of neuroleptic drugs. When not promptly recognized, this disease carries a high mortality (10%-20%) and morbidity rate. We report an unusual case of neuroleptic malignant syndrome that

Pedal edema associated with atypical antipsychotics.

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Prijava / prijava

This study describes a patient diagnosed as a case of bipolar affective disorder complaining of bothersome incidence of pedal edema 1 month after the initiation of atypical antipsychotic regimen with risperidone and quetiapine. All hematological and biochemical profiles were found to be normal. On

Self-limiting Atypical Antipsychotics-induced Edema: Clinical Cases and Systematic Review.

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Prijava / prijava

A number of atypical antipsychotics have been associated with peripheral edema. The exact cause is not known. We report two cases of olanzapine-induced edema and a brief review of atypical antipsychotic-induced edema, possible risk factors, etiology, and clinical features. The recommendation is

[Effect of neuroleptic, adreno- and cholinolytic agents on cerebral cortical function in edema].

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Prijava / prijava

Experiments on rats with experimental brain edema under water intoxication were made to study the effects of the neuroleptics aminazine and propazine, the central M-cholinoblocker amizyl and the alpha-adrenoblocker phentolamine on the time-course of the recovery of cortical electric activity after

Cardiovascular risk assessment of atypical antipsychotic drugs in a zebrafish model.

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Prijava / prijava

The zebrafish model has been developed and evaluated for its ability to predict the toxicity of chemicals. Zebrafish additionally serve as an excellent model for assessing drug-induced cardiotoxicity, although zebrafish and mammalian hearts differ in structure. Recently, regulatory authorities have

Correlations between different measures of antiserotonin activity of drugs. Study with neuroleptics and serotonin receptor blockers.

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Prijava / prijava

The antiserotonin properties of a series of neuroleptics, 5-HT-receptor blockers and some adrenoceptor antagonists were investigated in several in vivo test systems (L-5-HTP syndrome and 5-HT-paw edema in the rat) and in an in vitro test (isolated rat uterus preparation). The results were compared

Aripiprazole induced non-cardiogenic pulmonary edema: a case report.

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Prijava / prijava

Aripiprazole is a second-generation antipsychotic drug with partial dopamine agonistic activity. Although the adverse cardiovascular effects of both typical and atypical antipsychotics are well known, similar data on aripiprazole, which was recently introduced, are scarce. Herein we report a

Severe corneal edema after prolonged use of psychotropic agents.

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Prijava / prijava

A 23-year-old woman with schizophrenia who had been treated with a high dose of psychotropic agents for 6 years had bilateral corneal edema and suffered from severe visual disturbance. No signs of inflammation, infection, congenital abnormality, or corneal endotheliitis were observed. The symptoms

MRI white matter hyperintensity in neuroleptic malignant syndrome (NMS)--a clue to pathogenesis?

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Prijava / prijava

The case of a young female patient with neuroleptic malignant syndrome (NMS) and extended MRI white matter hyperintensity in the left parietal and both occipital lobes is reported. MRI lesions resembled findings in hypertensive encephalopathy, they were not readily compatible with CNS vasculitis.

Thiothixene induced edema.

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Prijava / prijava

The case described is of a woman who developed marked leg edema during thiothixene administration, and other cases of neuroleptic induced edema are reviewed. Possible mechanisms for the edema formation and clinical implications are discussed.

Pedal edema with olanzepine.

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Prijava / prijava

Olanzapine, an atypical antipsychotic is considered superior to its conventional congeners. Here we report two cases of pedal edema secondary to olanzapine. In both cases the systemic causes of pedal edema were ruled out. On reducing the dose of olanzapine, pedal edema regressed and completely

Olanzapine-induced tender pitting pre-tibial edema.

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Prijava / prijava

Antipsychotic-induced edema is uncommonly encountered in clinical practice. We report a case of tender pitting pre-tibial edema with olanzapine in a woman with no medical comorbidities. The peculiar distribution of edema resulted in diagnostic confusion necessitating specific investigations.

[Edema related to treatment with olanzapine].

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Prijava / prijava

OBJECTIVE In comparison to metabolic syndrome, edema seems to be a rare occurrence in antipsychotic treatment. METHODS In this paper, we report on two subjects with psychotic disorders who were found to have peripheral edema during olanzapine therapy. CONCLUSIONS The theoretical background and the

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