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atractylenolide ii/melanoma
Povezava se shrani v odložišče
3 rezultatov
Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Atractylenolide II (AT-II) is a sesquiterpene compound isolated from the dried rhizome of Atractylodes macrocephala (Baizhu in Chinese), which is traditionally prescribed for melanoma treatment by Chinese medicine practitioners. Our previous study showed that AT-II can inhibit B16 cells
Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Our previous studies showed that atractylenolide II (AT-II) has antimelanoma effects in B16 melanoma cells. In this study, we investigated the involvement of STAT3 signalling in the antimelanoma action of AT-II. Daily administration of AT-II (12.5, 25 mg/kg, i.g.) for 14 days significantly inhibited
Effects of sesquiterpenes isolated from largehead atractylodes rhizome on growth, migration, and differentiation of B16 melanoma cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The aims of this study were to isolate sesquiterpene compounds from the largehead atractylodes rhizome (LAR) and to investigate their effects on B16 cancer cells. A total of 8 sesquiterpenes from LAR were identified, of which eudesm-4 (15), 7-diene-9α, 11-diol (7) was isolated for the first time.
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