azadirachtin/nekroza

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Azadirachtin interacts with the tumor necrosis factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses.

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Prijava / prijava

The role of azadirachtin, an active component of a medicinal plant Neem (Azadirachta indica), on TNF-induced cell signaling in human cell lines was investigated. Azadirachtin blocks TNF-induced activation of nuclear factor kappaB (NF-kappaB) and also expression of NF-kappaB-dependent genes such as

Azadirachtin interacts with the tumor necrosis factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses.

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Anti-inflammatory and antinociceptive activities of azadirachtin in mice.

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Azadirachta indica (Meliaceae) extracts have been reported to exhibit anti-inflammatory and antinociceptive properties. However, the activities of azadirachtin, a limonoid and the major bioactive compound found in the extracts, have been poorly investigated in animal models. In the present study, we

Hepatoprotective activity of the neem-based constituent azadirachtin-A in carbon tetrachloride intoxicated Wistar rats.

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The aim of this study was to investigate the hepatoprotective role of azadirachtin-A in carbon tetrachloride (CCl4) induced hepatotoxicity in rats. The group allotment for the animals used in the hepatoprotective study included a vehicle treatment group, CCl4 (1 mL · (kg body mass)(-1)) treatment

Angiogenic and anti-inflammatory properties of azadirachtin A improve random skin flap survival in rats

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In plastic and reconstructive surgery, skin flap necrosis often occurs. How to improve the clinical application of skin flaps is a problem that people now look forward to solving. Drug therapy is one of the research focuses to improve skin flap survival. Our research found that Azadirachtin A

The effect of azadirachtin on the midgut histology of the locusts, Schistocerca gregaria and Locusta migratoria.

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The effects of azadirachtin on midgut cells of adult Schistocerca gregaria and Locusta migratoria were investigated by both light and electron microscopy. Pathological effects were seen in both species which could be related to dose and time after treatment. The midgut cells showed a slow necrosis,

Sustainable soil management practices and quality of potato grown on erodible lands.

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Land productivity can decline when top soil is lost. In Kentucky, limited resource farmers often produce vegetable crops on erodible lands. The objectives of this study were 1) to quantify the impact of three soil management practices (SMPs) on quantity of potato produced on erodible land, 2) to

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