Slovenian
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
betulonic acid/rak
Povezava se shrani v odložišče
Stran 1 iz 26 rezultatov
Boc-lysinated-betulonic acid: a potent, anti-prostate cancer agent.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Betulonic acid, derived from betulinol, a pentacyclic styrene, has shown a highly specific anti-prostate cancer activity in in vitro cell cultures. However, due to the lack of solubility of betulonic acid in aqueous medium, its potent anti-cancer activity in vivo has not been determined to the
X-ray diffraction and infrared spectroscopy of N,N-dimethylformamide and dimethyl sulfoxide solvatomorphs of betulonic acid.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
X-ray diffraction and infrared spectroscopy measurements for the N,N-dimethylformamide (DMF) and dimethyl sulfoxide (DMSO) solvatomorphs of betulonic acid (BA) were investigated. BA [3-oxolup-20(29)-en-28-oic acid, C(30)H(46)O(3)] exhibits a wide spectrum of biological activities and is considered
Employing rubusoside to improve the solubility and permeability of antitumor compound betulonic acid.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
OBJECTIVE
To examine if rubusoside (RUB) can overcome insolubility of betulonic acid (BEA), it can be accurately evaluated for its intrinsic activity against cancer in cell culture and in tumor animal models.
METHODS
By processing RUB and BEA together using a solvent evaporation method, a joint
Induction of intrinsic apoptosis in leukaemia stem cells and in vivo zebrafish model by betulonic acid isolated from Walsura pinnata Hassk (Meliaceae).
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Leukaemia stem cells (LSC) have been associated with disease relapse and chemotherapy resistance. Betulonic acid (BA), a pentacyclic lupane-type triterpenoid, was reported to exhibit cytotoxicity toward various cancer cells and to be capable of inducing intrinsic apoptosis in solid
Microbial transformations of two lupane-type triterpenes and anti-tumor-promoting effects of the transformation products.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Microbial transformation of betulin (1), a lupane-type triterpene obtained from the bark extract of white birch (Betula platyphylla Sukatshev var. japonica), and its chemical oxidation product, betulonic acid (2), by the fungus Chaetomium longirostre yielded
Triterpenoids Extracted from Rhus chinensis Mill Act Against Colorectal Cancer by Inhibiting Enzymes in Glycolysis and Glutaminolysis: Network Analysis and Experimental Validation.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Background:Rhus chinensis Mill is a traditional Chinese medicine (TCM) mostly used to treat several cancer types. Although previous studies have found that certain ingredients of R. chinensis such as flavonoids can inhibit tumor cell proliferation [e.g. colorectal cancer (CRC)],
Antitumor and antimetastatic effects of betulonic acid amides in mice with transplantable lewis carcinoma.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
We studied the effects of four synthetic amides of betulonic acid containing amino acid fragments (d,l-alpha-alanine, beta-alanine, and their methyl esters) on the rate of growth and metastatic dissemination of transplantable Lewis lung carcinoma in C57Bl/6 mice. The test compounds were administered
[Synthesis and antitumor activity of cyclopropane derivatives of betulinic and betulonic acids].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
New cyclopropane derivatives of betulin were synthesized by attachment of dichlorocarbenes or dibromocarbenes to the double bond of betulin diacetate, followed by the deprotection of hydroxyl groups. The betulin cyclopropane derivative was obtained from 20,29-dihydro-20,29-dichloromethylenebetulin
Paclitaxel and betulonic acid synergistically enhance antitumor efficacy by forming co-assembled nanoparticles
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The side effects and low bioavailability of paclitaxel (PTX) limit its clinical application. The formation of self-assembled nanomedicines without structural modification is attractive for biomedical applications. Here, we constructed a supramolecular co-assembled nanoparticles (NPs), which is
Biotransformation of betulinic and betulonic acids by fungi.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Betulinic acid (1), a triterpenoid found in many plant species, has attracted attention due to its important pharmacological properties, such as anti-cancer and anti-HIV activities. The closely related, betulonic acid (2) also has similar properties. In order to obtain derivatives potentially useful
Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Structural modification was performed at the C-28 position of betulonic acid (BetA). Twenty-five BetA derivatives were synthesized, and evaluated for their antitumor activities against MGC-803, PC3, Bcap-37, A375, and MCF-7 human cancer cell lines by MTT assay. Among the derivatives, most of the
Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Natural products, including plants, microorganisms and marines, have been considered as valuable sources for anticancer drug discovery. Many Chinese herbs have been discovered to be potential sources of antitumor drugs.
METHODS
In the present study, we investigated the antitumor efficacy
Synthesis, Anticancer and Antibacterial Activity of Betulinic and Betulonic Acid C-28-Triphenylphosphonium Conjugates with Variable Alkyl Linker Length.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The synthetic transformation and modification of natural products with the aim to improve the biological properties is an area of current interest. The triterpenoids betulin and betulinic acid are very abundant in nature and now are commercially available. In our study, starting from betulin and
[Synthesis and Anticancer Activity of Betulonic Acid Imidazolides].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Synthesis of lupane C28-imidazolides, contained 3-oxo-, 3-oximino- and 2-cyano-2,3-seco-4(23)-en-frag ments in cycle A was carried out. The most antitumor activity at. in vitro testing showed 3-oximino-lup- 20(29)-en-28-yl-1H-imidazole-1-carboxylate; which inhibited the growth or induced apoptosis
Najbolj popolna baza zdravilnih zelišč, podprta z znanostjo
- Deluje v 55 jezikih
- Zeliščna zdravila, podprta z znanostjo
- Prepoznavanje zelišč po sliki
- Interaktivni GPS zemljevid - označite zelišča na lokaciji (kmalu)
- Preberite znanstvene publikacije, povezane z vašim iskanjem
- Iščite zdravilna zelišča po njihovih učinkih
- Organizirajte svoje interese in bodite na tekočem z raziskavami novic, kliničnimi preskušanji in patenti
Vnesite simptom ali bolezen in preberite o zeliščih, ki bi lahko pomagala, vnesite zelišče in si oglejte bolezni in simptome, proti katerim se uporablja.
* Vse informacije temeljijo na objavljenih znanstvenih raziskavah
