Age-matched controls with normal hearing or mild sensorineural hearing loss: 40 decibel or less in better hearing ear, and normal vestibular function

Moderate Sensorineural hearing loss: 41-60 decibel in the better hearing ear

Severe Sensorineural hearing loss: 61-80 decibel in the better hearing ear

Bilateral vestibulopathy: half with normal hearing, half with severe to profound sensorineural hearing loss

Hearing Loss, Sensorineural

Bilateral Vestibulopathy

Alzheimer Disease

Mild Cognitive Impairment

Longitudinal hearing, vestibular and cognitive follow-up

Longitudinal follow-up

University Hospital Antwerp

Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects

Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects: Correlation With Cortical Auditory Evoked Potentials and MRI Brain Volume Changes

Cognitive test adapted for hearing impaired subjects, minimum score is 200, maximum score is 800, higher scores indicate better cognitive performance

Ethisch Comité, UZA

Prof. dr. Vincent Van Rompaey, principal investigator

University Hospital, Antwerp

Universiteit Antwerpen

Patients with bilateral vestibulopathy, according to the Barany Criteria (2017, Strupp).

Subjects without vestibular or neurological diseases (DHI<5), and with normal hearing thresholds according to their age.

Vestibular Disorder

Cognitive tasks for respectively: general cognition and spatial cognition

RBANS-H, virtual Morris Water Maze

Antwerp University Hospital

Hearing Loss, Vestibular Loss and Cognitive Performance

The Link Between Hearing Loss, Vestibular Loss and Cognitive Performance: Cross-sectional Data in Patients With Bilateral Vestibulopathy

General cognitive assessment, cfr. Claes et al 2016. The total-score is standardized with a mean of 100 and a standard deviation of 15. The higher the total score, the better the cognition of the participant.

Spatial cognition assessment, cfr. Hamilton. Path length and latency are recorded, the higher the worse the spatial cognition of the participant.

Cfr. Claes et al 2016. The subscale are standardized with a mean of 100 and standard deviation of 15. The higher the score, the better the performance on a specific subdomain of cognition (attention, immediate memory, delayed memory, visuospatial and language)

Principal Investigator

Vestibular Abnormality

Vestibular Cochlear Implant Hearing Impaired Child

Vestibular Function in Cochlear Implanted Hearing Impaired Children

Clinical test which assesses vestibuloocular (VOR) function in which examiner briskly rotate patient's head to both sides while patient fixate his eyes on a target and watch for corrective saccades on eye movements.

Clinical balance test which assesses vestibulospinal (VSR) function, patient stand on a firm surface and on a soft cushion with eyes closed and eye open, a scoring system is obtained for all these balance situations.

Objective test of VOR, includes irrigation of warm and\or cool water into patient's external auditory canal and measure the resulting nystagmus by a computerized system.

Objective test of vestibulocollic (VCR) function which assesses otolithic organs, VEMPs amplitudes and latencies are measured by a computerized system.

bilateral vestibulopathy/gluhost

Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects

Hearing Loss, Vestibular Loss and Cognitive Performance

Vestibular Cochlear Implant Hearing Impaired Child

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