boldo/glutathione

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Peumus boldus attenuates copper-induced toxicity in Drosophila melanogaster.

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Prijava / prijava

Peumus boldus (P. boldus) is a medicinal plant popularly used in the treatment of gastrointestinal disorders. P. boldus aqueous extract is rich in phenolic compounds and alkaloids that possess antiinflammatory and antioxidant effects. In the present study, the potential protective effect of P.

Low doses of ethanolic extract of Boldo (Peumus boldus) can ameliorate toxicity generated by cisplatin in normal liver cells of mice in vivo and in WRL-68 cells in vitro, but not in cancer cells in vivo or in vitro.

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OBJECTIVE Use of cisplatin, a conventional anticancer drug, is restricted because it generates strong hepatotoxicity by accumulating in liver. Therefore its anticancer potential can only be fully exploited if its own toxicity is considerably reduced. Towards this goal, ethanolic extract of the

Impacts of Strain Variation on Response to Heat Stress and Boldo Extract Supplementation to Broiler Chickens.

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Prijava / prijava

There is increasing interest in the use of natural antioxidant supplements in poultry diets as protection against the adverse effects of heat stress. The potential protective effect of boldo (Peumusboldus molina) leaf extract, which have antioxidant activity, were investigated against

Chemoprotective activity of boldine: modulation of drug-metabolizing enzymes.

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Possible chemoprotective effects of the naturally occurring alkaloid boldine, a major alkaloid of boldo (Peumus boldus Mol.) leaves and bark, including in vitro modulations of drug-metabolizing enzymes in mouse hepatoma Hepa-1 cell line and mouse hepatic microsomes, were investigated. Boldine

Boldine enhances bile production in rats via osmotic and farnesoid X receptor dependent mechanisms.

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Boldine, the major alkaloid from the Chilean Boldo tree, is used in traditional medicine to support bile production, but evidence to support this function is controversial. We analyzed the choleretic potential of boldine, including its molecular background. The acute- and long-term effects of

Protective effect of boldine on oxidative mitochondrial damage in streptozotocin-induced diabetic rats.

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Increased oxidative stress has been suggested to be involved in the pathogenesis and progression of diabetic tissue damage. Several antioxidants have been described as beneficial for oxidative stress-associated diseases. Boldine ([s]-2,9-dihydroxy-1, 10-dimethoxyaporphine) is a major alkaloid found

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