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bronchiectasis/glutathione

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8 rezultatov

Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Neutrophil-derived myeloperoxidase (MPO) is recognized as a major source of oxidative stress at the airway surface of a cystic fibrosis (CF) lung where, despite limited evidence, the antioxidant glutathione is widely considered to be low. The aims of this study were to establish whether oxidative

Systemic deficiency of glutathione in cystic fibrosis.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Cystic fibrosis (CF), a disorder characterized by mutations of the CF transmembrane regulator gene, is characterized in the lung by chronic inflammation, leading to progressive damage to the airway epithelium, bronchiectasis, and chronic obstructive lung disease. One process contributing to the

Cellular and plasma oxidative stress biomarkers are raised in adults with bronchiectasis.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
OBJECTIVE Oxidative stress is believed to play an important role in the pathophysiology of bronchiectasis. The aims of this study were to evaluate the oxidative stress status in bronchiectasis patients. METHODS This cross-sectional study included 90 clinically stable adults with bronchiectasis of
BACKGROUND Sulfur mustard (SM) is a strong alkylating agent that causes acute and chronic effects on different organs following exposure. Main late respiratory complications are chronic obstructive pulmonary disease, bronchiectasis, asthma, and bronchiolitis obliterans. It seems that oxidative

Role of neutrophils in mediating human epithelial cell detachment from native basement membrane.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Epithelial cell detachment from underlying basement membrane is a feature of diseases of many organs. In the lungs it is seen in disorders as diverse as bronchiectasis, allograft rejection, and asthma. The potential for different leukocytes to induce this change is not clear. In asthma both

Study of human epithelial cell detachment and damage: effects of proteases and oxidants.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Polymorphonuclear leucocyte (PMN) accumulation is associated with damage to airways epithelial cells in bronchitis, bronchiectasis and some forms of asthma. PMNs release several molecules which may mediate this damage, particularly proteases and oxidants. Using an in vitro model of intact human

Plasma oxidant-antioxidant status in different respiratory disorders.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
This study confirms the fact that in different respiratory disorders, the status of plasma oxidants and antioxidants shifts from normal. The status of oxidants in plasma as represented by malondialdehyde (MDA) levels increased significantly in the conditions of chronic obstructive pulmonary disease

Antioxidant supplementation for lung disease in cystic fibrosis.

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Airway infection leads to progressive damage of the lungs in cystic fibrosis (CF) and oxidative stress has been implicated in the etiology. Supplementation of antioxidant micronutrients (vitamin E, vitamin C, beta-carotene and selenium) or N-acetylcysteine (NAC) as a source of
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