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bruceantin/brucea antidysenterica
Povezava se shrani v odložišče
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Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Bruceantin, purified from an Ethiopian plant used to treat dysentery, killed Entamoeba histolytica in vitro (IC50 [the concentration of drug which decreased the number of colonies to half that of controls] = 0.018 microgram/ml). Six related quassinoids of 17 tested were also amoebicidal. No
Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Antitumor activity of bruceantin: an old drug with new promise.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Bruceantin was first isolated from Brucea antidysenterica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice. Phase I and II clinical trials were then initiated, but no objective tumor regressions were
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