calcinosis/phosphatase

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Tumoral calcinosis with hyperphosphatemia.

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Prijava / prijava

Tumoral calcinosis is a rare disorder of mineral metabolism among adolescents and young adults characterized by deposition of calcific masses around large joints. It is less commonly reported in pediatric population and commonly mistaken for bone tumors. Typical lab parameters include

Evaluation of vascular calcinosis risk factors in patients on chronic hemodialysis: lack of influence of calcium carbonate.

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Prijava / prijava

Linear calcifications of the abdominal aorta and of the iliac and femoral arteries were measured yearly for 3 years on X rays of 24 patients on chronic hemodialysis taking variable amounts of calcium carbonate and Al(OH)3 but no pharmacological doses of vitamin D or 1 alpha-hydroxylated vitamin D

Clinical and genetic analysis of idiopathic normophosphatemic tumoral calcinosis in 19 patients.

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Prijava / prijava

Tumoral calcinosis is a rare clinicopathological entity characterized by ectopic soft-tissue calcification, typically periarticular. Normophosphatemic tumoral calcinosis is seldom reported in East Asian populations, and the preoperative diagnosis is often elusive. This study was

Idiopathic calcinosis cutis of the scrotum: a case report and review of the literature.

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Prijava / prijava

Abnormal deposition of calcium in the skin or subcutaneous tissue is termed calcinosis cutis. Idiopathic calcinosis cutis of the scrotum is an uncommon entity. The pathogenesis of idiopathic calcinosis cutis of the scrotum is debatable. The condition presents as several brown to

[Phosphorus metabolism in a case of tumoral calcinosis].

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Prijava / prijava

Hyperphosphataemia with levels of 65 mg/l was found in a black African aged 20 with a 10-year history of tumour calcinosis. Levels of blood calcium, plasma ionised calcium, serum alkaline phosphatase, 24-hour urinary calcium and phosphate were all normal, as was renal function. Tubular phosphate

A dose- and time-controllable syngeneic animal model of breast cancer microcalcification.

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Prijava / prijava

The development of novel diagnostic agents for the detection of breast cancer microcalcifications requires a reliable animal model. Based on previous work from our group, we hypothesized that a single systemic injection of recombinant bone morphogenetic protein-2 (rBMP-2) could be used to create

[Cutaneous or subcutaneous calcinosis observed in leprosy patients. 1. Clinical observations].

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Prijava / prijava

A roentgenographic examination was made for the limbs of leprosy patients with calcinosis in whom atrophic cutaneous sclerosis and subcutaneous induration or infiltration were observed. The observation results are summarized as follows. 1. Atrophic cutaneous sclerosis was one of a sequela in

Tumoral calcinosis: light and electron microscopic study with electron diffraction and x-ray microanalysis of the mineral deposit.

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Prijava / prijava

Samples of deposits taken from sites close to articulations in a young black African suffering from tumoral calcinosis with hyperphosphoraemia were studied by light and electron microscopy techniques. Light microscopy demonstrated lesions of a foreign body granuloma type in contact with calcium salt

Familial tumoral calcinosis in two Chinese patients: a case series.

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Prijava / prijava

BACKGROUND Tumoral calcinosis is a rare and benign condition characterized by massive subcutaneous soft tissue deposits of calcium phosphate predominantly around large joints. METHODS Familial tumoral calcinosis was present in two members of a Han Chinese family, namely, the son and daughter. The

High dietary phosphate intake induces development of ectopic calcifications in a murine model of familial tumoral calcinosis.

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Prijava / prijava

Familial tumoral calcinosis is characterized by ectopic calcifications due to persistent hyperphosphatemia. The most common genetic cause of the disease is mutations in GALNT3, encoding a glycosyltransferase involved in a posttranslational modification of fibroblast growth factor 23 (FGF23). The

Mechanisms of pathologic calcification.

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Prijava / prijava

Pathologic calcification usually is initiated by the biologic membranes of mitochondria or matrix vesicles. Mitochondria frequently initiate intracellular calcification. Matrix vesicles, derived from the outer membrane of cells by budding or cell disruption, initiate extracellular calcification in

Multifocal tumoral calcinosis in a 4-year-old girl.

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Prijava / prijava

METHODS Female, 4 FINAL DIAGNOSIS: Tumoral calcinosis Symptoms: Hard immobile mass Medication: - Clinical Procedure: - Specialty: Surgery. OBJECTIVE Congenital defects. BACKGROUND Tumoral calcinosis is an uncommon condition associated with the deposition of painless calcific masses. It is more

Tumoral calcinosis in the neck.

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Prijava / prijava

Tumoral calcinosis manifests soft-tissue calcification, usually near major joints. It variably includes hyperphosphatemia, elevated 1,25-dihydroxycalciferol, and an affected sibling. Serum calcium, alkaline phosphatase, and parathyroid hormone are normal. Tumoral calcinosis of the head and neck is

Effect of a purified diet on dystrophic cardiac calcinosis in mice.

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Prijava / prijava

Male and female C3H/HeNCrl mice were divided into test groups and fed either a purified diet (AIN-76A) or a natural ingredient diet (NIH-07). Lesions of dystrophic cardiac calcinosis (DCC) were found to be more prevalent and more severe in mice fed the purified diet. The cardiac changes, which were

Intracellular precipitation of hydroxyapatite mineral and implications for pathologic calcification.

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Prijava / prijava

In contrast to physiologic biomineralization occurring in bones, teeth and otoconia in vertebrates, calcification of soft tissues occurs in many pathologic conditions. Although similarities have been noted between the two processes, and despite the important clinical consequences of ectopic

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