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cerebroside/asthenia
Povezava se shrani v odložišče
3 rezultatov
Adult-onset metachromatic leukodystrophy presenting as isolated peripheral neuropathy.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A 38-year-old man presented with weakness of the lower limbs. Electrophysiology revealed a pronounced demyelinating neuropathy. Nerve biopsy disclosed de- and remyelinating lesions and characteristic lamellar inclusions in Schwann cells and macrophages. There was no familial history of neurologic
Sulfatide storage in neurons causes hyperexcitability and axonal degeneration in a mouse model of metachromatic leukodystrophy.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Metachromatic leukodystrophy is a lysosomal storage disorder caused by deficiency in the sulfolipid degrading enzyme arylsulfatase A (ASA). In the absence of a functional ASA gene, 3-O-sulfogalactosylceramide (sulfatide; SGalCer) and other sulfolipids accumulate. The storage is associated with
Paranodal junction formation and spermatogenesis require sulfoglycolipids.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Mammalian sulfoglycolipids comprise two major members, sulfatide (HSO3-3-galactosylceramide) and seminolipid (HSO3-3-monogalactosylalkylacylglycerol). Sulfatide is a major lipid component of the myelin sheath and serves as the epitope for the well known oligodendrocyte-marker antibody O4.
Najbolj popolna baza zdravilnih zelišč, podprta z znanostjo
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- Zeliščna zdravila, podprta z znanostjo
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* Vse informacije temeljijo na objavljenih znanstvenih raziskavah
