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clerodane diterpene/rak dojke
Povezava se shrani v odložišče
3 rezultatov
Epoxy clerodane diterpene inhibits MCF-7 human breast cancer cell growth by regulating the expression of the functional apoptotic genes Cdkn2A, Rb1, mdm2 and p53.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Systematic analyses of plants that are used in traditional medicine may lead to the discovery of novel cytotoxic secondary metabolites. Diterpene possesses multiple bioactivities; here, epoxy clerodane diterpene (ECD) was isolated from Tinospora cordifolia (Willd.) stem and shown potential
Crispene E, a cis-clerodane diterpene inhibits STAT3 dimerization in breast cancer cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Crispene E, a new clerodane-type diterpene, inhibited STAT3 dimerization in a cell-free fluorescent polarisation assay and was found to have significant toxicity against STAT3-dependent MDA-MB 231 breast cancer cell line and selectively inhibited the expression of STAT3 and STAT3 target genes cyclin
A New Cytotoxic Clerodane Diterpene from Casearia graveolens Twigs.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1
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