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colonic polyps/protease

Povezava se shrani v odložišče
ČlankiKliničnih preskušanjPatenti
8 rezultatov
Objective: To investigate the activities of gelatinases (matrix metalloproteinase [MMP]-2 and MMP-9) and serine proteases in the colorectal mucosa of Miniature Dachshunds (MDs) with inflammatory colorectal polyps (ICRPs).
Early and effective detection of cancers of the gastrointestinal tract will require novel molecular probes and advances in instrumentation that can reveal functional changes in dysplastic and malignant tissues. Here, we describe adaptation of a wide-field clinical fiberscope to perform wide-field
Pentosan polysulphate (PPS), a highly negatively charged polysaccharide, is a significant inhibitor of an isoenzymic form of a cell surface protease referred to as guanidinobenzoatase GB, associated with colonic carcinoma tissues in frozen sections and free GB in solution, in a

[Protease activities in gastric and colon cancer tissues].

Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Activities of cathepsin B, cathepsin L, and plasminogen activators (urinary type plasminogen activator and tissue type plasminogen activator) were assayed in homogenates of cancer tissue, normal tissue closely surrounding the cancer tissue, and normal tissue distant from the cancer tissue from 30
Purpose: Exosomal proteases are important in regulation of molecular signaling from growth factor receptors andadhesion molecules and also the regulation of cell motility and protein folding. The aim of this study was to evaluatethe level of ADAM10, ADAM17 and 20S proteasomes in exosomes isolated
A 100 fold increase in plasma protease activity (p less than 0.001) was found in 9 of 12 individuals with heritable adenomatosis of the colon and rectum (ACR). The three patients lacking increased protease activity showed 400% more plasmin inhibitor activity compared to controls. The 9 ACR patients
Tumor-associated trypsin inhibitor (TATI) is a 6 K dalton protease inhibitor, that was isolated from urine of a patient with ovarian cancer. In our experience, mean serum level of TATI in healthy subjects (n. 120), is 13 micrograms/l (range 5.1-42 micrograms/l). The cut-off point is established in
Pathways of the molecular pathogenesis of colorectal carcinoma have been extensively studied and molecular lesions during the development of the disease have been revealed. High up in the list of colorectal cancer lesions are APC (adenomatous polyposis coli), K-ras, Smad4 (or DPC4-deleted in
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