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10 rezultatov
Effects of saffron and its constituents, crocin-1, crocin-2, and crocetin on α-synuclein fibrils.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Saffron, the stigma of Crocus sativus Linné (Iridaceae family), has been known to inhibit aggregation of β-amyloid, a nerve tissue protein. α-Synuclein (αS) is a 140-amino acid protein found abundantly in various regions of the brain. Its abnormal aggregation and accumulation in nerve tissue are
Regulated preparation of crocin-1 or crocin-2' triggered by the co-solvent DMSO using Bs-GT/At-SuSy one-pot reaction.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Crocins are the primary coloring ingredients of saffron. The low-glycosylated members of this compound family, such as crocin-1(crocetin mono-glucosyl ester) and crocin-2' (crocetin di-glucosyl ester), are rarely distributed in nature and attracting interest in their therapeutic uses. In our
The effects of crocin on the symptoms of depression in subjects with metabolic syndrome.
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Prijava / prijava
BACKGROUND
Studies have suggested that metabolic syndrome (MetS) is associated with increased depressive symptoms, and reducing depression in subjects with MetS is important. Crocin, an active component of saffron, has useful properties for subjects with MetS, including antidepressant
Simultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatography.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A simple, sensitive and specific high-performance liquid chromatography-UV (HPLC-UV) method has been developed for the first time to simultaneously quantify the five major biologically active ingredients of saffron, namely crocin 1, crocin 2, crocin 3, crocin 4 and crocetin. Calibration curves were
[In vitro evaluation of the chemopreventive potential of saffron].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Cancer is a very important national health problem in Mexico, while a significant increase in the total and childhood cancer mortality has been recorded during the last decades. Chemoprevention, defined as the use of natural or synthetic agents to prevent or to block the development of cancer in
Protective effects of saffron and its active components against oxidative stress and apoptosis in endothelial cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In this study, we investigated the role of mitogen-activated protein kinase (MAPK) signaling pathways in mediation of the protective effects of saffron extract, saffron essential oil, safranal and crocin on bovine aortic endothelial cells against oxidative injury. The viability of cells in response
Structural characterization of highly glucosylated crocins and regulation of their biosynthesis during flower development in Crocus.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Crocin biosynthesis in Crocus has been proposed to proceed through a zeaxanthin cleavage pathway catalyzed by carotenoid cleavage dioxygenase 2 (CCD2), and followed by glucosylation reactions catalyzed by CsGT2 (UGT74AD1). In Crocus ancyrensis flowers, crocins with eight (crocin-1), seven
Discrimination of Different Parts of Saffron by Metabolomic-Based Ultra-Performance Liquid Chromatography Coupled with High-Definition Mass Spectrometry.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In this study, the metabolite profiling of three different parts of Crocus sativus L. was measured by using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTof-MS/MS). Multivariate statistical analysis was used to distinguish among the samples from
Antidepressant properties of bioactive fractions from the extract of Crocus sativus L.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The aim of this study was to investigate the antidepressant properties of stigmas and corms of Crocus sativus L. The aqueous ethanol extract of C. sativus corms was fractionated on the basis of polarity. Among the different fractions, the petroleum ether fraction and dichloromethane fraction at
Effects of crocin analogs on ocular blood flow and retinal function.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Ischemic retinopathy and age-related macular degeneration are the leading ocular diseases that cause blindness. The etiology of these diseases is due in part to the reduction of blood flow in the retina and/or choroid. Crocin analogs isolated from Crocus sativus L. were found to significantly
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