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endodermal sinus tumor/hypoxia
Povezava se shrani v odložišče
3 rezultatov
Apurinic/apyrimidinic endonuclease expression in pediatric yolk sac tumors.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
The enzyme apurinic/apyriminidic endonuclease/redox factor 1 (Ape1/ref1), a key protein in the base excision repair pathway, displays repair and redox activity. We examined the role of Ape1/ref1 and a protein it regulates, hypoxia inducible factor 1 alpha (HIF-1 alpha) in pediatric yolk
The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Hypoxia promotes stem cell maintenance and tumor progression, but it remains unclear how it regulates long-term adaptation toward these processes. We reveal a striking downregulation of the hypoxia-inducible histone H3 lysine 9 (H3K9) demethylase JMJD1A as a hallmark of clinical human germ
Prognostic value of intratumoral carbonic anhydrase IX expression in testicular germ cell tumors.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Testicular germ cell tumors (TGCTs) represent a highly curable malignancy, however a small proportion of patients fails to be cured with cisplatin-based chemotherapy. Carbonic anhydrase IX (CA IX) is upregulated by hypoxia in several cancer types and correlates with a poor prognosis. The present
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