ent clerodane/croton

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New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & M. G. Gilbert.

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Prijava / prijava

The roots of the endangered medicinal plant Croton megalocarpoides collected in Kenya were investigated and twenty-two compounds isolated. Among them were twelve new ent-clerodane (1-12) and a new abietane (13) diterpenoids, alongside the known crotocorylifuran (4 a), two known abietane and four

Ent-clerodane and ent-trachylobane diterpenoids from Croton dictyophlebodes

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Prijava / prijava

The stem bark and root bark extracts of Croton dictyophlebodes (Euphorbiaceae) yielded seven undescribed ent-clerodanes: 15,16-epoxy-17,12(S)-olide-ent-cleroda-1,3,13(16),14-tetraen-18-oic acid methyl ester (crotodictyo A), 3β,4β:15,16-diepoxy-ent-cleroda-13(16),14-dien-20-al (crotodictyo B),

Ent-Clerodane Diterpenes from the Bark of Croton oligandrus Pierre ex Hutch. and Assessment of Their Cytotoxicity against Human Cancer Cell Lines.

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Prijava / prijava

New clerodane diterpenes, 12-epi-megalocarpodolide D (2) and an epimeric mixture of crotonolins A (3) and B (4), were isolated from the bark of Croton oligandrus following a bioassay-guided isolation protocol. Known compounds, megalocarpodolide D (1), 12-epi-crotocorylifuran (5), cluytyl-ferulate

Cytotoxic diterpenoids from the leaves and stem bark of Croton haumanianus (Euphorbiaceae)

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Prijava / prijava

The leaf extract of Croton haumanianus J. Léonard (Euphorbiaceae) yielded twenty-six compounds, including eight previously reported ent-kauranes and an ent-labdane and eight undescribed ent-kauranes, ent-16R-kauran-17-al, ent-3β-hydroxy-16R-kauran-17-al, ent-16S,17-epoxykauran-19-ol,

Laevinoids A and B: two diterpenoids with an unprecedented backbone from Croton laevigatus.

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Prijava / prijava

Chemical fractionation of the ethanolic extract of a Chinese herbal plant, Croton laevigatus, yielded laevinoids A (1) and B (2) with a new rearranged ent-clerodane scaffold named as laevinane. The structures of 1 and 2 were assigned on the basis of detailed spectroscopic analyses with their

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