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feminization/hypoxia

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ČlankiKliničnih preskušanjPatenti
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The "estrogen paradox" in pulmonary arterial hypertension (PAH) refers to observations that while there is a higher incidence of idiopathic PAH in women, rodent models of PAH show male dominance and estrogens are protective. To explain these differences, we previously proposed the

Altered adult sexual behavior in the male rat following chronic prenatal hypoxia.

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Prijava / prijava
The last week of gestation is a critical period for the sexual differentiation of the brain in the rat. Exposure to prenatal stress during this period has been shown to demasculinize and/or feminize adult male sexual behavior. Many of the neurochemical and endocrine responses to hypoxia are similar

Differential vulnerability of male and female rats to the timing of various perinatal insults.

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Prijava / prijava
The results of five experiments showed that exposure to diazepam, hypoxia and monosodium glutamate during the prenatal or early postnatal period of rapid brain development may result in different behavioral consequences depending on the timing of the exposure rather than the nature of the agent.

Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations.

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Prijava / prijava
BACKGROUND Leydig cell tumors (LCTs) are the most common non-germ-cell neoplasms of the testis. LCTs are often hormonally active and can result in precocious virilization or in adult feminization. We identified an LCT in an affected individual from a kindred with hereditary leiomyomatosis and renal
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