frugoside/calotropis

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Cytotoxic cardenolides from the leaves of Calotropis gigantea.

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Prijava / prijava

Two 15beta-hydroxycardenolides (1,2) and a 16alpha-hydroxycalactinic acid methyl ester (3) along with eleven known compounds including 16alpha-hydroxycalotropagenin, coroglaucigenin, 16alpha-hydroxycalotropin, calactinic acid, calotoxin, 6'-O-(E-4-hydroxycinnamoyl)desglucouzarin,

Cytotoxic principles of a Bangladeshi crude drug, akond mul (roots of Calotropis gigantea L.).

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Prijava / prijava

Three cardenolide glycosides, calotropin (1), frugoside (2), and 4'-O-beta-D-glucopyranosylfrugoside (3), were obtained as the cytotoxic principles of "akond mul" (roots of Calotropis gigantea L.). The cytotoxicity of these compounds against various cell lines of human and mouse origin was tested.

Proceraside A, a new cardiac glycoside from the root barks of Calotropis procera with in vitro anticancer effects.

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Prijava / prijava

We have studied the ethyl acetate fraction of the methanolic extract of the root barks of Calotropis procera (Asclepiadaceae) from Egypt. Bioassay-directed fractionation and final purification of the extract resulted in the identification of a new cardenolide glycoside named proceraside A (1)

Molecular docking of the anticancer bioactive compound proceraside with macromolecules involved in the cell cycle and DNA replication.

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Prijava / prijava

The bioactive compounds proceraside A, frugoside and calotropin, which were extracted from the root bark of Calotropis procera (Aiton) W.T. Aiton (family Asclepiadaceae), were recently reported to inhibit the growth of inhibition against various human cancer cell lines in vitro. However, their modes

Calotropis gigantiea (L.) R. Br (Apocynaceae): a phytochemical and pharmacological review.

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Prijava / prijava

BACKGROUND Calotropis gigantiea (L.) R. Br (Apocynaceae) commonly called as "crown flower" or "giant milk weed" is a well-known weed to many cultures for treating various disorders related to central nervous system, skin diseases, digestive system, respiratory system, reproductive system etc.

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