indole 3 carboxaldehyde/rak dojke

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Fate of indole-3-carbinol in cultured human breast tumor cells.

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Prijava / prijava

Indole-3-carbinol (I3C), a natural component of Brassica vegetables, is a promising cancer preventive agent that can reduce the incidence of tumors in reproductive organs when administered in the diet. Here we report on the metabolic fate of radiolabeled I3C in MCF-7 cells. I3C was surprisingly

Novel bis(indolyl)hydrazide-hydrazones as potent cytotoxic agents.

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Prijava / prijava

A series of bis(indolyl) hydrazide-hydrazones 5a-n were synthesized and evaluated for their cytotoxicity against selected human cancer cell lines. The reaction of indole-3-carboxaldehyde 2 with indole-3-carbohydrazide 4 in presence of catalytic amount of acetic acid afforded 5a-n in good yields.

Design and efficient synthesis of pyrazoline and isoxazole bridged indole C-glycoside hybrids as potential anticancer agents.

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Prijava / prijava

C-glycosides are important class of molecules exhibit diverse biological activities and present as structural motif in many natural products. Two series of new pyrazoline and isoxazole bridged indole C-glycoside molecular hybrids (n = 36) were efficiently synthesized starting from diverse indole

Synthesis, Molecular Docking and Biological Evaluation of Novel Flavone Derivatives as Potential Anticancer Agents Targeting Akt.

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Prijava / prijava

Flavonoids are naturally occurring compounds with versatile health-promoting effects against various diseases.To synthesize and evaluate biological activity of novel flavone derivatives against cancer.A new series of

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Herbal & Natural Medicine

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