lactose intolerance/protease

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Susceptibility of lactase to luminal proteases in developing rat intestine.

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Prijava / prijava

BACKGROUND Postnatal development of rat intestine is associated with a decline in brush-border lactase activity. This phenomenon is similar to the adulthood hypolactasia in humans. However, the mechanism underlying this process is not understood. METHODS The effect of luminal proteases from adult

Molecular Characterization and In Vitro Analyses of a Sporogenous Bacterium with Potential Probiotic Properties.

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Prijava / prijava

The Gram-positive thin rods of a Bacillus species were identified and designated as Bacillus coagulans RK - 02 through the standard microbiological and biochemical characterization procedures, followed by data analysis and comparison with the characteristics given in Bergey's manual of systematic

Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management.

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Prijava / prijava

Strategies to avoid lactose malabsorption, which affects 70% of the world's population, are focused on the restriction of milk and dairy products or the use of non-human β-galactosidases or probiotics endowed with β-galactosidase activity added at mealtime. Our evaluation of a commercial blend of

Hormone induced expression of brush border lactase in suckling rat intestine.

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Prijava / prijava

The postnatal development of intestine is associated with a decline in brush border lactase activity in rodents. This is similar to adulthood hypolactasia, a phenomenon prevalent in humans worldwide. In the present study, the effect of luminal proteases from adult rat intestine was studied in vitro

[Rotaviruses in human and veterinary medicine].

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Prijava / prijava

Rotaviruses are the commonest cause of diarrhea and are responsible for more than 25% of all deaths from diarrhea worldwide. Children become infected early in life and most infections in infants older than 3 months are symptomatic. These viruses account for 18 million cases of moderate or severe

In vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tract.

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Prijava / prijava

Exogenous enzymes are administered orally to treat several diseases, such as pancreatic insufficiency and lactose intolerance. Due to the proteinaceous nature of enzymes, they are subject to inactivation and/or digestion in the gastrointestinal (GI) tract. Here we describe a convenient

Influence of duodenal secretions and its components on release and activities of human brush-border enzymes.

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Prijava / prijava

The in vitro effects of human duodenal secretions and various combinations of its components on activity and release of enzymes from the human brush border were examined. Sucrase retained activity for 90 min in duodenal secretions, and maltase was almost as stable; lactase lost activity rapidly and

Carboxymethylpachymaran entrapped plant-based hollow microcapsules for delivery and stabilization of β-galactosidase.

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Prijava / prijava

β-Galactosidase (β-Gal) as a dietary supplement can alleviate symptoms of lactose intolerance. However, β-Gal is deactivated due to the highly acidic conditions and proteases in the digestive tract. In this work, β-Gal was encapsulated into L. clavatum sporopollenin exine capsules (SECs) to

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