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The effect of preservatives and dilution on the deterioration of Russian thistle (Salsola pestifer), a pollen extract.

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Prijava / prijava

The Role of FAT10 in Alcoholic Hepatitis Pathogenesis

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Prijava / prijava

FAT10 expression is highly up-regulated by pro-inflammatory cytokines IFNγ and TNFα in all cell types and tissues. Increased FAT10 expression may induce increasing mitotic non-disjunction and chromosome instability, leading to tumorigenesis. In this review, we summarized others' and our work on

Germination and population structure of spear thistle Cirsium vulgare in relation to experimentally controlled sheep grazing.

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The size and number of rosettes of Cirsium vulgare were censused in a 4 ha sheep grazing trial on lowland calcareous grassland in paddocks receiving controlled winter, spring and summer grazing treatments. Spring grazing significantly increased thistle rosette numbers, and there were always fewer

Therapeutic efficacy of silymarin from milk thistle in reducing manganese-induced hepatic damage and apoptosis in rats.

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Oxidative stress has been proposed as a possible mechanism involved in manganese (Mn) toxicity. Using natural antioxidants against metal-induced hepatotoxicity is a modern approach. The present study investigated the beneficial role of silymarin, a natural flavonoid, in Mn-induced hepatotoxicity

Silibinin Improves TNF-α and M30 Expression and Histological Parameters in Rat Kidneys After Hepatic Ischemia/Reperfusion.

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BACKGROUND Remote kidney damage is a sequel of hepatic ischemia-reperfusion (I/R) injury. Silibinin is the main ingredient of the milk thistle plant seed extract with known antioxidant and hepatoprotective activity. Our study investigates the nephroprotective potential of intravenously administered

Chalcone synthase genes from milk thistle (Silybum marianum): isolation and expression analysis.

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Silymarin is a flavonoid compound derived from milk thistle (Silybum marianum) seeds which has several pharmacological applications. Chalcone synthase (CHS) is a key enzyme in the biosynthesis of flavonoids; thereby, the identification of CHS encoding genes in milk thistle plant can be of great

Silibinin attenuates MPP⁺-induced neurotoxicity in the substantia nigra in vivo.

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Parkinson's disease (PD) is characterized by degeneration of the nigrostriatal dopaminergic (DA) pathway. The cause of neuronal death in PD is largely unknown, but it is becoming clear that inflammation plays a significant role in the pathophysiology of PD. Silibinin is a major flavonoid in milk

Hepatoprotective effect of commercial herbal extracts on carbon tetrachloride-induced liver damage in Wistar rats.

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BACKGROUND Various hepatoprotective herbal products from plants are available in Mexico, where up to 85% of patients with liver disease use some form of complementary and alternative medicine. However, only few studies have reported on the biological evaluation of these products. OBJECTIVE Using a

Testing the limits of resistance: a 19-year study of Mediterranean grassland response to grazing regimes.

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A synthesis of a long-term (19 years) study assessing the effects of cattle grazing on the structure and composition of a Mediterranean grassland in north-eastern Israel is presented, with new insights into the response of the vegetation to grazing management and rainfall. We hypothesized that the

Sylimarin as hepatic protector and immunomodulator in Nile tilapia during Streptococcus agalactiae infection.

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This study investigated the use of silymarin, an extract obtained from the milk thistle (Silybum marianum) and its effects as a possible hepatoprotector in Nile tilapia (Oreochromis niloticus). Silymarin was used as feed additive to the diet at a concentration of 0.1% (1 kg per ton of dry ration)

Studies of allergen extract stability: the effects of dilution and mixing.

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BACKGROUND However potent the allergy extracts provided by manufacturers, they are subject to deterioration with storage, especially after dilution or mixture with other extracts. OBJECTIVE This study was performed to assess separately the deterioration during storage in allergen extract potency

A Comprehensive Updated Review of Pharmaceutical and Nonpharmaceutical Treatment for NAFLD.

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Prijava / prijava

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the western world with prevalence of 20-33%. NAFLD comprises a pathological spectrum. Nonalcoholic fatty liver (NAFL) is at one end and consists of simple hepatic steatosis. On the contrary, nonalcoholic steatohepatitis

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