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maytansine/maytenus
Povezava se shrani v odložišče
7 rezultatov
Spatial profiling of maytansine during the germination process of Maytenus senegalensis seeds.
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Prijava / prijava
The ecological role of maytansine, an important antineoplastic and antimicrobial compound with high cytotoxicity, particularly as a chemical defense compound has remained elusive since its discovery in the 1970s in Maytenus and Putterlickia plants. In the present study, we have used
[Studies on the antitumor constituents of Maytenus confertiflora Luo et Chen (Celastraceae). II. Isolation and characterization of maytansine and maytanprine from the stems].
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Prijava / prijava
Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus.
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Prijava / prijava
Occurrence and non-detectability of maytansinoids in individual plants of the genera Maytenus and Putterlickia.
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Prijava / prijava
Individual plants belonging to different species of the family Celastraceae collected from their natural habitats in South Africa (Putterlickia verrucosa (E. Meyer ex Sonder) Szyszyl., Putterlickia pyracantha (L.) Szyszyl., Putterlickia retrospinosa van Wyk and Mostert) and Brazil (Maytenus
Cytotoxic activity of maytanprine isolated from Maytenus diversifolia in human leukemia K562 cells.
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Prijava / prijava
We examined the cytotoxic effect of maytanprine isolated from the methanol extract of Maytenus diversifolia on human leukemia K562 cells using a flow cytometer and compared its cytotoxicity with that of maytansine, a potent cytotoxic maytansinoid. Maytanprine at concentrations of 0.03 nM or more (up
[Investigating cytostatic substances in tissue of plants Maytenus Molina in in-vitro cultures. II. chromatographic test of extracts from callus of Maytenus wallichiana R. et B].
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Prijava / prijava
Maytenus wallichiana callus tissue was extracted. The extract was fractionated to achieve maytansine containing residue. In none of the fractions maytansine corresponding substance was found. However evaluation by Tetrahymena test indicated strong cytotoxicity (ID50 1.8 micrograms/cm3).
Antitumor agents, 112. Emarginatine B, a novel potent cytotoxic sesquiterpene pyridine alkaloid from Maytenus emarginata.
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Prijava / prijava
A new sesquiterpene pyridine alkaloid, emarginatine B [2] has been isolated, along with maytansine [3], from Maytenus emarginata. Emarginatine B showed potent cytotoxicity against human KB cells (ED50 = 0.4 micrograms/ml). Spectral correlations established its structure as a 9-benzoate and C-8
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