miliusa elongata/antimikotik

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Inhibition of the Calcineurin Pathway by Two Flavonoids Isolated from Miliusa sinensis Finet & Gagnep.

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In order to discover plant-derived signaling pathway inhibitors with antifungal properties, a two-component screening system utilizing the calcineurin and Hog1 mitogen-activated protein kinase pathways responsible for the virulence networks of Cryptococcus neoformans was employed, owing to the

Cananginones A–I, linear acetogenins from the stem bark of Miliusa velutina [corrected].

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Nine linear C23 and C21 acetogenins, named cananginones A-I (1-9), were isolated from stem bark of Miliusa velutina [corrected] . Their structures were established by spectroscopic methods. These compounds showed cytotoxicity against three cancer cell lines (KB, MCF7 and NCI-H187) with IC₅₀ values

Genus Miliusa: A Review of Phytochemistry and Pharmacology.

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Background

Genus Miliusa (family Annonaceae), widely distributed in mainland Asia and Australia to New Guinea, has been employed in both traditional herbal uses and pharmacological medicines. Original research articles related to this genus are now available, but

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Herbal & Natural Medicine

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