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morroniside/ishemija
Povezava se shrani v odložišče
5 rezultatov
Neuroprotective effect of morroniside on focal cerebral ischemia in rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Cornus officinalis Sieb. et Zucc., known as Shan-zhu-yu in Chinese, has been used to treat cerebrovascular disease and diabetes in Traditional Chinese Medicine for a long time and morroniside is the main component of Shan-zhu-yu. In this study, we examined whether morroniside could protect
Promoting neurogenesis via Wnt/β-catenin signaling pathway accounts for the neurorestorative effects of morroniside against cerebral ischemia injury.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Ischemic stroke is a leading cause of mortality and permanent disability in adults worldwide. Neurogenesis triggered by ischemia in the adult mammalian brain may provide insights into stroke treatment. Morroniside is an active component of sarcocarp of C. officinalis that have shown neuroprotective
Morroniside promotes angiogenesis and further improves microvascular circulation after focal cerebral ischemia/reperfusion.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Preservation of cerebral microvascular functional integrity is crucial for protecting and repairing the brain after stroke. Our previous study demonstrated that morroniside promoted angiogenesis 7days after stroke. The current study aimed to further evaluate the long-term effects of morroniside on
Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Treating the vascular elements within the neurovascular unit is essential for protecting and repairing the brain after stroke. Acute injury on endothelial systems results in the disruption of blood-brain barrier (BBB), while post-ischemic angiogenesis plays an important role in delayed functional
Morroniside protects against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The aim of the present study was to investigate the effect of morroniside against matrix metalloproteinase (MMP)2/9 and focal cerebral ischemia/reperfusion (I/R) injury in rats. A rat model of focal cerebral I/R injury rats was established and rats were administered with 30, 90 or 270 mg/kg/day
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