neuroectodermal tumors primitive/protease

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Mutation analysis and loss of heterozygosity of PEDF in central nervous system primitive neuroectodermal tumors.

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Prijava / prijava

Deletion of 17p is the most frequent abnormality observed in central nervous system (CNS) primitive neuroectodermal tumors (PNETs), implicating the presence of a tumor suppressor gene which maps to 17p. The gene for pigment epithelium-derived factor (PEDF) has been cloned and mapped to 17p13. PEDF

Protein Profiling of the Supratentorial Primitive Neuroectodermal Tumor (PNET) Cell Line PFSK-1.

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Prijava / prijava

Supratentorial primitive neuroectodermal tumors (PNETs) are rare embryonal cerebral hemispheric tumors proposed to arise from primitive neuroepithelial cells. The permanent cell line PFSK-1 is widely used in studies of this tumor entity and it was the aim of this study to generate a

Successful treatment of primitive neuroectodermal tumor-associated microangiopathy with multiple bone metastases.

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Prijava / prijava

We report here a 16-year-old male with primitive neuroectodermal tumor (PNET)-associated probable microangiopathy with multiple bone metastases. Laboratory findings excluded the possibility of amegakaryocytic or immune thrombocytopenia and/or disseminated intravascular coagulation. He was first

Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness.

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Prijava / prijava

Patients with primary brain tumors have bleak prognoses and there is an urgent desire to identify new markers for sensitive diagnosis and new therapeutic targets for effective treatment. A family of proteins, the disintegrin and metalloproteinases (ADAMs or adamalysins), are cell surface and

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