pachypodol/pogostemon cablin

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Pachypodol, a Methoxyflavonoid Isolated from Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation.

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Oxidative stress has been implicated in the pathogenesis of many diseases including chronic liver diseases. Nrf2 is a master transcriptional factor regulating the induction of cellular antioxidant defense systems. Here, the Nrf2-activating effect of the crude methanol extract of dried leaves of

[Chemical constituents of Pogostemon cablin (Blanco) Benth].

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Nine compounds were isolated from the herb of Pogostemon cablin. They were identified as patchouli alcohol (1), pogostone (2), friedelin (3), epifriedelinol (4), pachypodol (5), retusine (6), oleanolic acid (7), beta-sitosterol (8) and daucosterol (9) on the basis of spectral data (1H-NMR, IR, MS

Anti-emetic principles of Pogostemon cablin (Blanco) Benth.

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Bioassay-guided fractionation of anti-emetic extracts and constituents of 8 traditional Chinese herbal drugs was performed. Twenty extracts described in Table 1 showed anti-emetic activity on copper sulfate induced-emesis in young chicks. From the n-hexane extract of Pogostemon cablin, patchouli

[Study on constituents of the aerial parts of Pogostemon cablin].

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OBJECTIVE To investigate the chemical constituents of the aerial parts of Pogostemon cablin. METHODS The constituents were isolated by column chromatography over silica gel, Sephadex LH-20 and C8. Structures were identified by spectroscopic data analysis. RESULTS Thirteen compounds were obtained and

Antimutagenic activity of flavonoids from Pogostemon cablin.

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A methanol extract from Pogostemon cablin showed a suppressive effect on umu gene expression of SOS response in Salmonella typhimurium TA1535/pSK1002 against the mutagen 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (furylfuramide). The methanol extract was re-extracted with hexane, dichloromethane,

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