phenylcarboxylic acid/sepsa

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Normal level of sepsis-associated phenylcarboxylic acids in human serum.

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Prijava / prijava

Previous studies showed that large amounts of phenylcarboxylic acids (PhCAs) are accumulated in a septic patient's blood due to increased endogenous and microbial phenylalanine and tyrosine biotransformation. Frequently, biochemical aromatic amino acid transformation into PhCAs is considered

Trace enrichment of phenylcarboxylic acids from a model biological fluid and serum of human blood.

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Prijava / prijava

The study was focused on the development of a solid-phase extraction protocol for seven phenylcarboxylic acids from albumin solutions by using unmodified hyper-cross-linked polystyrene restricted access materials with crosslinking degrees varying from 100 to 400% (four of the acids are known to be

Microbial origin of phenylcarboxylic acids in the human body.

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Prijava / prijava

In previous studies we demonstrated increased amounts of phenylcarboxylic acids (PCA) in serum of patients with sepsis. This observation prompted the present study of the ability of the human microbiome bacteria to produce PCA in vitro. PCA were detected in culture media by gas chromatography-mass

Microextraction of aromatic microbial metabolites by packed hypercrosslinked polystyrene from blood serum.

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Prijava / prijava

The article is devoted to the application of modern sample preparation technique - microextraction by packed sorbent (MEPS) - in conjunction with non-conventional type of sorbent - hypercrosslinked polystyrene, that was investigated for the first time in this work. Their combination was used to

EFFECT OF CARBOXYLIC ACIDS OF GUT MICROBIAL ORIGIN ON HOST CELL PROLIFERATION IN ORGANOTYPIC TISSUE CULTURES.

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Prijava / prijava

Intestinal microbiota produces many carboxylic acids, especially short chain fatty acids (SCFA) as a result of carbohydrates, fats and proteins fermentation and which are intermediates in the interaction of the microbiota and the host. SCFA (formate, acetate, propionate, butyrate) are formed by the

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