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phyllanthoside/rak
Povezava se shrani v odložišče
5 rezultatov
Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Fifty-eight cell lines in the National Cancer Institute drug screen were analyzed for their ability to efflux the fluorescent dye rhodamine 123 as a functional assay for P-glycoprotein (Pgp). Using flow cytometry, the rhodamine fluorescence was measured for each cell line under four incubation
Disposition and metabolism of the antitumor glycoside phyllanthoside in mouse and beagle dog.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Phyllanthoside is a naturally occurring glycoside with activity against IP transplantable murine tumors. Phyllanthoside administered IV, to mice at a nontoxic dose of 16 mg/kg could not be detected in blood or plasma even 30 s after administration. There was rapid formation of a less polar
Medicinal plants in tropical medicine. 2. Natural products in cancer treatment from bench to the clinic.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The development of anticancer agents has, in the past, relied heavily on leads derived from screening a wide variety of agents from both synthetic and natural sources. With the development of new techniques of measurement of biochemical changes in cells and the advent of molecular biological
Structure-activity relationships for osmium(II) arene phenylazopyridine anticancer complexes functionalised with alkoxy and glycolic substituents
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Twenty-four novel organometallic osmium(II) phenylazopyridine (AZPY) complexes have been synthesised and characterised; [Os(η6-arene)(5-RO-AZPY)X]Y, where arene = p-cym or bip, AZPY is functionalized with an alkoxyl (O-R, R = Me, Et, nPr, iPr, nBu) or
Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The National Cancer Institute (NCI) Human Tumor Cell Line Anti-Cancer Drug Screen has evaluated the cytotoxicity profiles of a large number of synthetic compounds, natural products, and plant extracts on 60 different cell lines. The data for each compound/extract can be assessed for similarity of
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