pyruvate kinase/krvavitev

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Administration of ATP-MgCl2 following hemorrhage and resuscitation increases hepatic phosphoenolpyruvate carboxykinase and decreases pyruvate kinase activities.

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Prijava / prijava

Since administration of ATP-MgCl2 following trauma and hemorrhagic shock improves tissue perfusion as well as cell and organ function, the aim of this study was to determine whether this agent has any salutary effects on the hepatic rate-controlling enzymes specific for gluconeogenesis, such as

Faecal pyruvate kinase isoenzyme type M2 for colorectal cancer screening: a meta-analysis.

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Prijava / prijava

OBJECTIVE To present a critical discussion of the efficacy of the faecal pyruvate kinase isoenzyme type M2 (faecal M2-PK) test for colorectal cancer (CRC) screening based on the currently available studies. METHODS A literature search in PubMed and Embase was conducted using the following search

Metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis

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Prijava / prijava

Very little is known about the role of metabolic regulatory mechanisms in platelet activation and thrombosis. Dimeric pyruvate kinase M2 (PKM2) is a crucial regulator of aerobic glycolysis that facilitates the production of lactate and metabolic reprogramming. Herein, we report that limiting PKM2

ADP receptor antagonists and converting enzyme systems reduce platelet deposition onto collagen.

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Prijava / prijava

The effect of the ADP receptor antagonists ATP and adenosine 5'-(beta, gamma-methylene)triphosphate (AMP-PCP), and the ADP-utilizing enzyme systems creatine phosphokinase/creatine phosphate (CPK/CP) and pyruvate kinase/phosphoenol pyruvate (PK/PEP) on platelet deposition onto type I collagen was

Hepcidin and Anemia: A Tight Relationship.

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Prijava / prijava

Hepcidin, the master regulator of systemic iron homeostasis, tightly influences erythrocyte production. High hepcidin levels block intestinal iron absorption and macrophage iron recycling, causing iron restricted erythropoiesis and anemia. Low hepcidin levels favor bone marrow iron supply for

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