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4 rezultatov
A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A tumor-specific, bcr-abl-derived fusion peptide vaccine can be safely administered to patients with chronic myelogenous leukemia (CML) and can elicit a bcr-abl peptide-specific T-cell immune response. In the present phase 2 trial, 14 patients with CML in chronic phase were vaccinated with 6 fusion
The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Cancer cells are characterized by uncontrolled replication involving loss of control of cyclin dependent kinases (CDKs) and cyclins, and by abolished differentiation. In this study we introduce KGI, which is a nanoparticle with a Quillaja saponin as an active molecule. By the use of RNA array
Development of a genetically engineered vaccine against feline leukemia virus infection.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A genetically engineered subunit vaccine against FeLV infection was developed. The protective immunogen in the vaccine was a purified recombinant protein containing the entire amino acid sequence of FeLV subgroup A gp70 envelope protein. The optimal adjuvant was determined to be a highly purified
Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Saponin fractions of Quillaja saponaria Molina (QS) have cytotoxic activity against cancer cells in vitro, but are too toxic to be useful in the clinic. The toxic effect was abolished by converting QS fractions into stable nanoparticles through the binding of QS to cholesterol. Two fractions of QS
Najbolj popolna baza zdravilnih zelišč, podprta z znanostjo
- Deluje v 55 jezikih
- Zeliščna zdravila, podprta z znanostjo
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