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rosmarinic acid/gluhost
Povezava se shrani v odložišče
3 rezultatov
The Antioxidant Effect of Rosmarinic Acid by Different Delivery Routes in the Animal Model of Noise-Induced Hearing Loss.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
OBJECTIVE
Trans-tympanic Rosmarinic Acid (RA), as compared with the systemic administration, protects against noise-induced auditory hair cell and hearing losses in rats in vivo.
BACKGROUND
ROS production, lipoperoxidative damage, and an imbalance of antioxidant defences play a significant role in
Rosmarinic acid up-regulates the noise-activated Nrf2/HO-1 pathway and protects against noise-induced injury in rat cochlea.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Noise-induced hearing loss depends on progressive increase of reactive oxygen species and lipoperoxidative damage in conjunction with the imbalance of antioxidant defenses. The redox-sensitive transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) plays a critical role in the
Rosmarinic acid, active component of Dansam-Eum attenuates ototoxicity of cochlear hair cells through blockage of caspase-1 activity.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Cisplatin causes auditory impairment due to the apoptosis of auditory hair cells. There is no strategy to regulate ototoxicity by cisplatin thus far. Dansam-Eum (DSE) has been used for treating the central nerve system injury including hearing loss in Korea. However, disease-related scientific
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