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sampangine/cryptococcosis
Povezava se shrani v odložišče
3 rezultatov
Microbial transformation of sampangine.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Microbial transformation studies of the antifungal alkaloid sampangine (2) have revealed that it is metabolized by a number of microorganisms. Using a standard two-stage fermentation technique, Beauvaria bassiana (ATCC 7159), Doratomyces microsporus (ATCC 16225), and Filobasidiella neoformans (ATCC
Characterization of the major metabolite of sampangine in rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Sampangine (1) is a plant-derived antifungal copyrine alkaloid extracted from the stem bark of Cananga odorata. Although it possesses potent in vitro antifungal activity, 1 is devoid of significant and reproducible in vivo activity in a mouse model of cryptococcosis. Speculating that the lack of in
Discovery of Simplified Sampangine Derivatives with Potent Antifungal Activities against Cryptococcal Meningitis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Cryptococcal meningitis (CM) is associated with high morbidity and mortality. Current antifungal drug therapy for CM has the following challenges: limited efficacy, significant side effects, emerging drug resistance, and unavailability in highly needed countries. There is an urgent need to develop
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