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sanguinarine/vnetje
Povezava se shrani v odložišče
Stran 1 iz 79 rezultatov
Investigation of sanguinarine and chelerythrine effects on LPS-induced inflammatory gene expression in THP-1 cell line.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine have been used in folk medicine for their wide range of useful properties. One of their major effect is also anti-inflammatory activity, that is not clarified in detail. This study focused on the ability of these alkaloids to
Sanguinarine suppresses IgE induced inflammatory responses through inhibition of type II PtdIns 4-kinase(s).
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The effects of sanguinarine on IgE mediated early signaling mechanisms leading to inflammatory mediators release were investigated. Pretreatment of RBL 2H3 cells with sanguinarine inhibited IgE induced activation of type II PtdIns 4-kinase activity. Concomitant with type II PtdIns 4-kinase
Sanguinarine Attenuates Lipopolysaccharide-induced Inflammation and Apoptosis by Inhibiting the TLR4/NF-κB Pathway in H9c2 Cardiomyocytes.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The inflammatory response is involved in the pathogenesis of the most common types of heart disease. Sanguinarine (SAN) has various pharmacological properties such as anti-inflammatory, antioxidant, antibacterial, antitumor, and immune-enhancing properties. However, few studies have investigated the
Anti-inflammatory and neuroprotective effects of sanguinarine following cerebral ischemia in rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Stroke is one of the leading causes of mortality worldwide. Protective agents that can diminish injuries caused by cerebral ischemia-reperfusion (I/R) are important in alleviating the harmful outcomes of stroke. The aim of the present study was to investigate the protective role of sanguinarine in
Pharmacokinetic and anti-inflammatory effects of sanguinarine solid lipid nanoparticles.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The sanguinarine (SG) was studied for its pharmacokinetic and anti-inflammatory activities with prepared solid lipid nanoparticles (SLNs). The sanguinarine solid lipid nanoparticles (SG-SLNs) were prepared by film-ultrasonic dispersion method and the entrapment efficiency of SG was higher at 75.6 %.
The anti-inflammatory effects of sanguinarine and its modulation of inflammatory mediators from peritoneal macrophages.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The quaternary ammonium salt, sanguinarine (SANG), is of great practical and research interest because of its pronounced, widespread physiological effects, which promote anti-microbial and anti-inflammatory responses in experimental animals. Sanguinarine was originally shown to possess
Sanguinarine protects against osteoarthritis by suppressing the expression of catabolic proteases.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Inflammatory cytokines play critical roles in the pathogenesis of osteoarthritis. Recent studies have demonstrated that natural active substances can serve as alternative therapeutic agents for the prevention and treatment of osteoarthritis. Sanguinarine, an alkaloid isolated from the roots of
Antioxidative activities of some chemotherapeutics. A possible mechanism in reducing gingival inflammation.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Inflammatory periodontal diseases are related to dental plaque formation. Increase in the perfusion of the inflamed tissue results in increased oxygen supply. Although oxygen has healing effects, it is bound to be a mediator of peroxidation in biological membranes. Chemotherapeutic agents such as
Antibacterial activity and mechanism of sanguinarine against Providencia rettgeri in vitro
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Background: Sanguinarine (SAG), a benzophenanthridine alkaloid, occurs in Papaveraceas, Berberidaceae and Ranunculaceae families. Studies have found that SAG has antioxidant, anti-inflammatory, and antiproliferative
Disposition of sanguinarine in the rat.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Sanguinarine is an alkaloid with known antibiotic and anti-inflammatory activity and its pharmacokinetics have been studied in the rat after a single oral dose (10 mg kg(-1) body weight). Alkaloid determination in the plasma and liver was carried out by high-performance liquid
Preparation, Characterization and Anti-Ulcer Efficacy of Sanguinarine Loaded Solid Lipid Nanoparticles.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
OBJECTIVE
This study was designed to develop sanguinarine-loaded solid lipid nanoparticles (SG-SLNs) and investigate its gastroprotective effect on ethanol-induced gastric mucosal lesions in mice.
METHODS
SG-SLNs were prepared by high temperature melt-cool solidification method using glycerol
Embryonic toxicity of sanguinarine through apoptotic processes in mouse blastocysts.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In this study, we examined the cytotoxic effects of sanguinarine, a phytoalexin with antimicrobial, anti-oxidant, anti-inflammatory and pro-apoptotic effects, on the blastocyst stage of mouse embryos, subsequent embryonic attachment and outgrowth in vitro and in vivo implantation via embryo
Hazardous effects of sanguinarine on maturation of mouse oocytes, fertilization, and fetal development through apoptotic processes.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Previously, we reported that sanguinarine, a phytoalexin with antimicrobial, anti-oxidant, anti-inflammatory and pro-apoptotic effects, is a risk factor for normal embryonic development that triggers apoptotic processes in the inner cell mass of mouse blastocysts, causing decreased embryonic
Sanguinarine is a potent inhibitor of oxidative burst in DMSO-differentiated HL-60 cells by a non-redox mechanism.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Sanguinarine (SA), a member of the benzo[c]phenanthridine isoquinoline alkaloids, has been shown to possess antimicrobial, anti-inflammatory, and antioxidant properties. We examined the effects of SA on oxidative burst in DMSO-differentiated HL-60 cells, an excellent model for studying oxidative
Sanguinarine-induced apoptosis: generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Sanguinarine is a benzophenanthridine alkaloid derived from the root of Sanguinaria canadensis and other poppy-fumaria species, possessing potent antibacterial, antifungal, and anti-inflammatory activities. In this study, we investigated the underling mechanisms by which sanguinarine induce
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