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Stran 1 iz 31 rezultatov
Ceruletide-induced acute pancreatitis in the dog and its amelioration by exogenous secretin.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Large pharmacological doses of ceruletide administered to conscious dogs by intravenous (i.v.) infusion uniformly induce a severe acute necrotizing pancreatitis within 4 h. High-dose i.v. secretin administered for a period of 24 h after cessation of ceruletide infusion resulted in a significant
Influence of secretin on the course of acute experimental pancreatitis in rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Inhibition of pancreatic secretion is a widely accepted therapeutical principle of acute pancreatitis. However, stimulation of water and bicarbonate secretion may be beneficial by washing out the ductular system in pancreatitis. Secretin (2 and 16 CU/kg body weight) or saline were given to rats at
Partial restoration of pancreatic function by exogenous secretin in rats with ceruletide-induced acute pancreatitis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Pharmacological doses of ceruletide administered intravenously to unconscious rats uniformly induces acute pancreatitis (AP) as well as a striking reduction in pure pancreatic juice (PPJ) and protein output. High-dose intravenous secretin administered to rats with ceruletide-induced AP effects a
Prospective evaluation of endoscopic ultrasonography, endoscopic retrograde pancreatography, and secretin test in the diagnosis of chronic pancreatitis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Chronic pancreatitis in its early stages may defy diagnosis despite existing diagnostic modalities. Endoscopic retrograde pancreatography (ERCP), secretin test, and conventional ultrasound are insensitive in detecting the early stages of chronic pancreatitis. The aim of this study was to
Pituitary adenylate cyclase activating-peptide and its receptor antagonists in development of acute pancreatitis in rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
OBJECTIVE
Pituitary adenylate cyclase activating-peptide (PACAP) is a late member of the secretin/glucagon/vasoactive intestinal peptide (VIP) family of brain-gut peptides. It is unknown whether PACAP takes part in the development of acute pancreatitis and whether PACAP or its antagonists can be
The role of cholecystokinin in the pathogenesis of acute pancreatitis in the isolated pancreas preparation.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In a variety of animal models of acute pancreatitis, cholecystokinin-receptor antagonists have ameliorated the injury response. These results suggest that cholecystokinin may play a primary role in the pathogenesis of pancreatitis initiated by multiple stimuli. In an effort to test this theory, a
The fluosol-perfused isolated canine pancreas: a model for the study of blood component effects in acute pancreatitis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Blood components have been implicated as factors which modulate organ injury in acute pancreatitis. To isolate these effects we compared a standardized isolated, blood-perfused, canine pancreas model as described by Herman-Taylor and modified by Cameron with a model using fluosol, a fluorocarbon, as
The effect of hypovolemic shock on pancreatic secretion.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A vascular pathogenesis of pancreatitis has been postulated in diabetics, the aged, Ortner's Syndrome, and various low-flow states. This report studies canine pancreatic secretion in a preparation of hypovolemic shock produced by controlled hemorrhage maintained for varying durations. Pancreatic
Pancreatitis as a complication of anticholinesterase insecticide intoxication.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Severe pancreatitis and a pseudocyst occurred in a patient following accidental ingestion of an anticholinesterase insecticide, a substance not previously known to produce pancreatitis. Experiments were done to elucidate the mechanism. In one group of dogs the pancreatic duct was perfused and
The intrahepatic biliary epithelium in the guinea pig: is hepatic artery blood flow essential in maintaining its function and structure?
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
To determine whether hepatic artery blood flow is essential in maintaining the function and structure of bile ductules/ducts, the acute effects of hepatic artery ligation on bile secretion and hepatic ultrastructure were examined in anesthetized, bile duct-cannulated guinea pigs. Sixty minutes after
Pancreatic exocrine secretion--a measure of the functional capacity of the pancreatic energy metabolism.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In studies on the pathogenesis of ischemic cell injury and of other pancreatic diseases the knowledge of the actual pancreatic energy state is an important factor. Therefore, it would be advantageous to have a simple and inexpensive method to determine this parameter and its alterations in the
Enterokinase.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Enterokinase is a glycoprotein and is now designated enteropeptidase (E.C.3.4.4.8.). It is present in the duodenal and jejunal mucosa. Pancreatic proteolytic enzymes are secreted as proenzymes. Enterokinase converts trypsinogen to trypsin in the duodenal lumen. Duodenopancreatic reflux of duodenal
Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Intracellular Ca(2+)-changes not only participate in important signaling pathways but have also been implicated in a number of disease states including acute pancreatitis. To investigate the underlying mechanisms in an experimental model mimicking human gallstone-induced pancreatitis, we ligated the
The effect of steroid administration on pancreatic secretion during and after hypovolemic shock.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In a previous report from this laboratory, 1 h of hypovolemia induced a significant decrease in pancreatic flow, bicarbonate and enzyme secretion. These parameters recover after restoration of blood volume, but never return to pre-shock levels. Furthermore, increasing the period of hypovolemia
Protective effects of therapy with a protease and xanthine oxidase inhibitor in short form pancreatic biliary obstruction and ischemia in rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The current study was done to evaluate the effects of short term (60 minutes) pancreatic biliary duct obstruction (PBDO) with intraductal hypertension (IDH) stimulated by secretin (0.2 clinical unit per kilogram per hour) and caerulein (0.2 microgram per kilogram per hour) plus 30 minutes of
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