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OBJECTIVE
To study the chemical constituents of the root of Stellera chamaejasme L.
METHODS
Various column chromatographies on silica gel and RP-18 were employed for isolation and purification. Structures of compounds were elucidated by spectral analysis.
RESULTS
Eight lignans and three biflavonoids
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BACKGROUND
Stellera chamaejasme is a perennial weed and is found across a wide geographic range. It is found in the Altai of eastern Russia, northern China and Mongolia southwards and reaches as far as the western Himalayas of the Qinghai-Tibet and Yungui Plateaus. The dried roots of S. Chamaejasme
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The genus Stellera comprises species of perennial herbs and shrubs, mainly distributed in the temperate regions of east Asia to west Asia. There are 10-12 species in the world, two species in China: S. chamaejasme and S. formosana Hayata. As recorded, the roots of Stellera species are
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Stellera chamaejasme L. (Thymelaeaceae) is widely distributed in Mongolia, Tibet and the northern parts of China. Its roots are commonly used as "Langdu", which is embodied in the Pharmacopoeia of the P.R. China (2010) as a toxic Traditional Chinese Medicine. It is claimed to have antivirus,
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