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4 rezultatov
Sweroside eradicated leukemia cells and attenuated pathogenic processes in mice by inducing apoptosis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Acute myeloid leukemia (AML), characterized by extremely heterogeneous molecular and biologic abnormalities, is an aggressive hematologic malignancy, hampering the research and development of effective targeted treatment modalities. Sweroside (SWE), an iridoid glycoside, is isolated from Lonicera
Studies on iridoid-related compounds. V. Antitumor activity of iridoid dervs. periodate oxidation products.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In the course of a modification study of iridoid glucosides to investigate their antitumor and antimicrobial activity, we found that about all metaperiodate oxidation products of iridoid glucosides which had no antitumor activity showed potent activity against the leukemia P388 in mice. They were
Cytotoxic activity of Guettarda pohliana Müll. Arg. (Rubiaceae).
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The cytotoxic activity of crude extracts and their fractions from leaves and roots of G. pohliana was assessed against nine human cancer cell lines: melanoma (UACC-62), breast (MCF-7), breast expressing the multidrug resistance phenotype (NCI-ADR), lung (NCI-460), prostate (PCO-3), kidney (786-0),
Induction of apoptosis in human pancreatic MiaPaCa-2 cells through the loss of mitochondrial membrane potential (ΔΨm) by Gentiana kurroo root extract and LC-ESI-MS analysis of its principal constituents.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The objective of the current study was to evaluate the methanolic root extract of Gentiana kurroo for antioxidant and antiproliferative activities as well as to study the effect of the extract on the induction of apoptosis in human pancreatic cancer cell line (MiaPaCa-2). The extract exerted
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