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totarol/tuberkuloza

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ČlankiKliničnih preskušanjPatenti
4 rezultatov

(+)-Totarol from Chamaecyparis nootkatensis and activity against Mycobacterium tuberculosis.

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Prijava / prijava
The isolation of (+)-totarol as active compound against Mycobacterium tuberculosis is reported from Chamaecyparis nootkatensis outerbark.

Totarol inhibits bacterial cytokinesis by perturbing the assembly dynamics of FtsZ.

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Prijava / prijava
Totarol, a diterpenoid phenol, has been shown to inhibit the proliferation of several pathogenic Gram-positive bacteria including Mycobacterium tuberculosis. In this study, totarol was found to inhibit the proliferation of Bacillus subtilis cells with a minimum inhibitory concentration of 2 microM.
The synergistic activity of antimycobacterial constituents from Saudi plants was evaluated in combination with isonicotinic acid hydrazide (INH) against four atypical organisms, namely, Mycobacterium intracellulare, M. smegmatis, M. xenopei and M. chelonei. The potency of INH was increased

Antimycobacterial terpenoids from Juniperus communis L. (Cuppressaceae).

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Prijava / prijava
BACKGROUND Juniperus communis is a plant which has been reported as a traditional cure for tuberculosis (TB) and other respiratory diseases. OBJECTIVE The aim of this study was to isolate and identify the constituents responsible for the activity of the n-hexane extract of Juniperus communis roots
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