15 rezultatov
A high prevalence of metabolic disease was evident in a large flock of sheep early in the lambing season. Pregnancy toxemia and secondary hypocalcemia were diagnosed on the basis of history, physical examination findings, and results of serum biochemical analyses. To decrease costs to the owner,
The specific activity of placental enzymes with a regulatory function in the pathways of glycolysis, gluconeogenesis, NADPH generation and fatty acid synthesis decrease during gestation in the rat. Similar decreases occur in the activity of enzymes of the human placenta when compared between early
At present, the conception of the use, efficacy and safety of hepatotropic agents in treatment of drug-induced liver injury, in particular due to antituberculosis drugs is not yet final, which is conditioned by extremely rare clinical trials on the subject adequate to the up-to-date principles of
Ever today diabetes and pregnancy constitute a high risk situation of the mother as well for the fetus, since still high maternal-fetal mortality rates are observed. A series of 134 diabetic women (99 type A, 15 type B, and 20 type C) were evaluated during pregnancy and delivery, and the results
At present the main problem in gestational diabetes (GDM) is that only less than 10% of the pregnant diabetics could be diagnosed and accordingly treated. Analysing 101 cases of pregnant diabetics we refer to the incidence of peripartal and perinatal complications. The treatment with insulin was
The clinical heterogeneity of Diabetes Mellitus (DM) is also evident during the gestational period and thus, pregnancy could be complicated by a previously diagnosed DM or by diabetes that is first diagnosed during pregnancy (gestational diabetes or gestational alteration of the oral glucose
Previous reports from this laboratory described animal experiments in which intravenous administration of fructose 1-6 diphosphate (FDP) at the onset of hypovolemia, toxemia, and trauma effected improvement in hemodynamic and metabolic parameters, attenuation of tissue damage, and a significant
The efficacy of albumin pretreated on carbohydrate adsorbents as a means of sorption detoxication was assessed in experimental postresuscitation toxemia and burn-induced trauma complicated by endogenous intoxication. It has been established that the use of highly effective "Albosorb" prevented the
The authors present the results of studies of the intensity of glycolytic oxidoreduction in the rat liver 3, 6, 12 and 24 days after the reproduction of experimental burn disease. This disease proved to lead to reduction of the glyceral-phosphate dehydrogenase activity and to decrease of
In order to evaluate the carbohydrate metabolic effects of certain drug therapies used in treating the toxemia syndrome, 75 term pregnant women were studied with two intravenous glucose tolerance tests performed 1 week apart. During the 2-hour tests, both blood glucose and plasma insulin were
Diseases of intermediary metabolism include ketosis and fatty liver of dairy cattle and pregnancy toxemia of ewes. These conditions occur when there is a failure of the homeostatic mechanisms regulating the mobilization of fats and the conservation of carbohydrates. The therapeutic approach is to