Early Diagnosis of Neonatal Sepsis
Fjalë kyçe
Abstrakt
Përshkrim
Sepsis is defined as a systemic inflammatory response syndrome (SIRS) associated with infection diagnosed either on microbiologic cultures or strong clinical evidence of an infection..Worldwide, neonatal sepsis is responsible for 4 million deaths annually and 99% of them occur in developing countries.. . morbidity associated with sepsis includes sensorineural hearing loss, visual disturbances, seizures, and neurodevelopmental issues.. Blood culture is considered as gold standard for diagnosis of sepsis. The ideal diagnostic test should be inexpensive, have quick results Hematologic scoring system(HSS) of Rodwell et al. includes the following: a) White blood cell and platelet count b) White blood differential count c) Nucleated red blood cell count (to correct WBC count) d) Assessment of neutrophil morphology for degenerative changes. A modified HSS(modified hematological scoring system) was developed by removing the repetitive parameters, adding a new parameter - nucleated RBC.
Datat
Verifikuar së fundmi: | 08/31/2019 |
Paraqitur së pari: | 09/23/2019 |
Regjistrimi i vlerësuar u dorëzua: | 09/23/2019 |
Postuar së pari: | 09/25/2019 |
Përditësimi i fundit i paraqitur: | 09/23/2019 |
Përditësimi i fundit i postuar: | 09/25/2019 |
Data e fillimit të studimit aktual: | 09/29/2019 |
Data e vlerësuar e përfundimit primar: | 09/29/2020 |
Data e vlerësimit të përfundimit të studimit: | 04/29/2021 |
Gjendja ose sëmundja
Ndërhyrja / trajtimi
Diagnostic Test: Blood culturs
Faza
Kriteret e pranimit
Gjinitë e pranueshme për studim | All |
Metoda e marrjes së mostrës | Non-Probability Sample |
Pranon Vullnetarë të Shëndetshëm | Jo |
Kriteret | Inclusion Criteria: - Newborns with history of prolonged rupture of membranes, maternal intrapartum fever or non specific signs of sepsis namely; neonatal fever or hypothermia , poor feeding ,lethargy, irritability, depressed neonatal reflexes ,respiratory distress including apnea or cyanosis,hypoxia,poor capillary perfusion,bradycardia,hypotension,pallor,edema,vomiting,diarrhea,abdominal distention, bulging anterior fontanelle,coma,seizures,unexplained jaundice, reduced suckling, bleeding problems,hypoglycemia,hyperglycemia or metabolic acidosis were included in the study Exclusion Criteria: - All the newborn babies with history of delayed cry, meconium aspiration, congenital anomaly, history of antibiotics administration prior to admission to the baby or mother, intrapartum and neonatal death in sibling with similar presentation will be excluded |
Rezultati
Masat Kryesore të Rezultateve
1. Early detection of neonatal sepsia [average 1 year]