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Effects of Oral Fruit Concentrate Supplementation on Cardiometabolic Parameters.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Lidhja ruhet në kujtesën e fragmenteve
StatusiRekrutimi
Sponsorët
University of Central Lancashire

Fjalë kyçe

Abstrakt

Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount. Dietary interventions to improve cardiometabolic health are highly sought after as they possess less risk than pharmacological drugs. Anthocyanins, found in high quantities in both tart cherries and blueberries are powerful antioxidants, that are potentially capable of improving cardiometabolic dysfunction. However, to date, no research has explored the cardiometabolic responses to tart cherry and blueberry supplementation.
Therefore, the primary purpose of the proposed investigation is to test the ability of oral tart cherry and blueberry supplementation to improve cardiometabolic parameters in healthy individuals.

Datat

Verifikuar së fundmi: 01/31/2020
Paraqitur së pari: 11/20/2019
Regjistrimi i vlerësuar u dorëzua: 11/21/2019
Postuar së pari: 11/25/2019
Përditësimi i fundit i paraqitur: 02/09/2020
Përditësimi i fundit i postuar: 02/11/2020
Data e fillimit të studimit aktual: 01/20/2020
Data e vlerësuar e përfundimit primar: 07/04/2021
Data e vlerësimit të përfundimit të studimit: 08/04/2021

Gjendja ose sëmundja

Metabolic Syndrome

Ndërhyrja / trajtimi

Dietary Supplement: Fruit concentrate - either cherry or blueberry

Faza

-

Grupet e krahëve

KrahNdërhyrja / trajtimi
Placebo Comparator: Placebo
Identical in taste and colour to the supplement juice, but with no anthocyanin content
Experimental: Cherry juice
30 mL of tart juice concentrate, which will be diluted with 100 mL of water - taken twice per day,
Experimental: Blueberry
30 mL of tart juice concentrate, which will be diluted with 100 mL of water - taken twice per day,

Kriteret e pranimit

Moshat e pranueshme për studim 18 Years Për të 18 Years
Gjinitë e pranueshme për studimAll
Pranon Vullnetarë të Shëndetshëmpo
Kriteret

Inclusion Criteria:

- Healthy

- 18 years of age and above

Exclusion Criteria:

- Pregnancy

- Diabetes or any other metabolic conditions

- Food allergies to cherries or blueberries

Rezultati

Masat Kryesore të Rezultateve

1. Change in blood pressure [20 days]

Systolic and diastolic blood pressure - measured using a digital blood pressure monitor

2. Change in % bodyfat [20 days]

Participants percentage composition of fat - measured using bio-electrical impedance

3. Change in waist to hip ratio [20 days]

Ratio of waist to hip circumference - measured using anthropocentric tape

4. Change in resting metabolic rate [20 days]

Estimated daily calorie usage (Kcal) at rest - obtained using a metabolic cart through indirect calorimetry.

5. Change in resting utilization of fats [20 days]

% contribution of fats to daily calories - at rest - obtained using a metabolic cart through indirect calorimetry.

6. Change in resting utilization of carbohydrates [20 days]

% contribution of carbohydrate to daily calories - at rest - obtained using a metabolic cart through indirect calorimetry.

7. Change in low intensity activity calories expended [20 days]

Estimated calorie usage (Kcal) during low intensity walking exercise - obtained using a metabolic cart through indirect calorimetry.

8. Change in low intensity activity utilization of fats [20 days]

% contribution of fats to calorie expenditure - during low intensity walking exercise - obtained using a metabolic cart through indirect calorimetry.

9. Change in low intensity activity utilization of carbohydrates [20 days]

% contribution of carbohydrates to calorie expenditure - during low intensity walking exercise - obtained using a metabolic cart through indirect calorimetry.

10. Change in low-moderate intensity activity calories expended [20 days]

Estimated calorie usage (Kcal) during low-moderate intensity walking exercise - obtained using a metabolic cart through indirect calorimetry.

11. Change in low-moderate intensity activity utilization of fats [20 days]

% contribution of fats to calorie expenditure - during low-moderate intensity walking exercise - obtained using a metabolic cart through indirect calorimetry.

12. Change in low-moderate intensity activity utilization of carbohydrates [20 days]

% contribution of carbohydrates to calorie expenditure - during low-moderate intensity walking exercise - obtained using a metabolic cart through indirect calorimetry.

13. Change in blood glucose [20 days]

Capillary blood glucose - mmol/L

14. Change in blood triglycerides [20 days]

Capillary blood triglycerides - mg/dl

15. Change in blood cholesterol [20 days]

Capillary blood cholesterol - mg/dl

16. Change in Coop-Wonka chart [20 days]

Psychological wellbeing - The Coop-Wonka chart is a six item questionnaire with a 1-5 scoring system for each thus the chart has a maximum score of 30 which indicates the lowest possible psychological Wellbeing.

17. Change in Beck Depression Inventory [20 days]

Psychological wellbeing - the Beck Depression Inventory is a 21 questionnaire with questions that range in scoring from 0-3, thus the maximum score is 63 which is the highest depression score possible.

18. Change in State Trait Anxiety Inventory [20 days]

Psychological wellbeing - the state trait anxiety inventory is a 40 item questionnaire with each question having a 1-4 score system, thus the maximum score is 80 which indicates the highest level of anxiety.

19. Change in Insomnia Severity Index [20 days]

Sleep quality - The Insomnia Severity Index is a brief instrument designed to assess the severity of both nighttime and daytime components of insomnia. The Insomnia Severity Index is a 7-item self-report questionnaire yielding a total score ranging from 0 to 28.

20. Change in Pittsburgh Sleep Quality Index [20 days]

Sleep quality - The Pittsburgh Sleep Quality index, is a questionnaire that consists of 19 self-rated questions, grouped into 7 components. Each component is scored separately, weighted equally on a 0 - 3 scale and the scores of the 7 components are then added to give a global score, which has a range of 0 - 21 with higher scores indicating worse sleep quality.

21. Change in Epworth Sleepiness Scale [20 days]

Sleep quality - The Epworth Sleepiness Scale is a self-administered questionnaire with 8 questions. Respondents are asked to rate, on a 4-point scale (0-3) with a maximum score of 24.

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