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Partial Pulpotomy on Caries Free Human Teeth

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Lidhja ruhet në kujtesën e fragmenteve
StatusiPërfunduar
Sponsorët
Islamic Azad University, Tehran

Fjalë kyçe

Abstrakt

The purpose of this study is to compare the human pulp response to partial pulpotomy using White ProRoot MTA or iRoot BP in the terms of dentinal bridge formation and inflammation.

Përshkrim

This will be a randomized single blind clinical trial. Setting and conduct: Twenty caries free premolar teeth from fifteen patients assigned for orthodontic extraction will be included. Participants including major eligibility criteria: Their parents need to sign an informed form, Patients shouldn't have any systematic complication, The teeth should be free of any symptom, caries and decalcification and should reveal a normal response to pulp sensitivity tests, No mobility or swelling in the surrounding soft tissues, sensitivity on palpation or percussion should be present. Intervention: A class one cavity will be prepared and the depth will be increased until the pulp exposure occurs. One millimeter of the coronal pulp will be removed. Then the exposure site will be covered using two pulpotomy agents: White ProRoot MTA as control group and iRoot BP. After six weeks (42 days) the teeth will be extracted after radiographic and clinical examination to find any sign of swelling, abscess or sinus tract. Main outcome measures (variables): The teeth will be sectioned and examined to compare the presence of dentinal bridge, its thickness and feature in the terms of tunnel defect formation. The underlying pulp will be assessed and graded according to the degree of inflammation as follows: grade 0 no inflammation, grade 1 mild inflammation, grade 2 moderate inflammations, grade 3 severe inflammation, grade 4 abscess formation or necrosis. Our criteria are based on ISO 7405.

Datat

Verifikuar së fundmi: 02/29/2012
Paraqitur së pari: 08/18/2011
Regjistrimi i vlerësuar u dorëzua: 08/18/2011
Postuar së pari: 08/21/2011
Përditësimi i fundit i paraqitur: 03/24/2012
Përditësimi i fundit i postuar: 03/26/2012
Data e fillimit të studimit aktual: 05/31/2011
Data e vlerësuar e përfundimit primar: 01/31/2012
Data e vlerësimit të përfundimit të studimit: 02/29/2012

Gjendja ose sëmundja

Dentin Bridge
Pulpitis

Ndërhyrja / trajtimi

Drug: Mineral Trioxide Aggregate

Drug: iRoot BP

Faza

Faza 2/Faza 3

Grupet e krahëve

KrahNdërhyrja / trajtimi
Active Comparator: Mineral Trioxide Aggregate
partial pulpotomy using White ProRoot MTA. Partial pulpotomy includes removal of 1mm of coronal pulp and covering the remaining tissue with a suitable material.
Drug: Mineral Trioxide Aggregate
partial pulpotomy using White ProRoot MTA. Partial pulpotomy includes removal of 1mm of coronal pulp and covering the remaining tissue with a suitable material.
Experimental: iRoot BP
Partial pulpotomy using iRoot BP. Partial pulpotomy includes removal of 1mm of coronal pulp and covering the remaining tissue with a suitable material. Bioaggregate is the first nano particle, water based root end filling material. This product includes calcium silicate, calcium hydroxide, hydroxy apatite and Tantalum oxide. Compared to MTA,this material lacks Bismuth oxide and calcium aluminate. iRoot BP is the injectable for of Bioaggregate (Injectable Root Bioaggregate Paste).
Drug: iRoot BP
Partial pulpotomy using iRoot BP. Partial pulpotomy includes removal of 1mm of coronal pulp and covering the remaining tissue with a suitable material. Bioaggregate is the first nano particle, water based root end filling material. This product includes calcium silicate, calcium hydroxide, hydroxy apatite and Tantalum oxide. Compared to MTA,this material lacks Bismuth oxide and calcium aluminate. iRoot BP is the injectable for of Bioaggregate (Injectable Root Bioaggregate Paste).

Kriteret e pranimit

Moshat e pranueshme për studim 10 Years Për të 10 Years
Gjinitë e pranueshme për studimAll
Pranon Vullnetarë të Shëndetshëmpo
Kriteret

Inclusion Criteria:

- Patients who are assigned to extract two premolar teeth in one jaw for orthodontic treatment plan.

- Their parents need to read and sign a fully informed form.

- They shouldn't have any systematic complication or take any medicine during the period of study.

- The teeth need to be free of any symptom, caries and decalcification

- They should give a normal response to pulp sensitivity tests (cold test) compared to the control tooth on the same quadrant.

- The teeth need to be free of mobility or swelling in the surrounding soft tissues and any sensitivity on palpation or percussion.

- On radiographic examination no apical lucency or PDL widening should be detected.

Exclusion Criteria:

- tooth crack

- tooth filling

- any caries

- hypocalcification

- The teeth showing apical lucency

- PDL widening on radiography

- sensitivity to cold, heat or bite

- The responses beyond the normal limits to pulp vitality testing

- Any medicine consumption

Rezultati

Masat Kryesore të Rezultateve

1. dentinal bridge formation [six weeks after intervention]

appearance of the dentinal bridge compared to normal dentin will be assessed under microscope

Masat dytësore të rezultateve

1. inflammatory status of the pulp [six weeks after intervention]

microscopic evaluation : inflammatory cell count and their distribution

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