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3 methoxybenzaldehyde/leukoza

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ArtikujProvat klinikePatentat
6 rezultatet
The title compounds having the structure of 2,3-diacetoxy-4-carbomethoxy-(3',5'-dioxo-N4'-substituted piperazinyl methyl) benzene were synthesized from 2-hydroxy-3-methoxybenzaldehyde in eight steps. Compound 9h showed a potent inhibitory effect against P388 leukemia cells in vitro.

Plasminogen activator and its enhancement in differentiating mouse Friend erythroleukemia cells.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Urokinase-type plasminogen activator (u-PA) activity was found in the medium as well as in the lysates of cultured uninduced Friend leukemia (FL) cells. PA activity progressively increased during the cell differentiation induced by dimethyl sulphoxide (DMSO), 4-hydroxy-3-methoxybenzaldehyde or

Anti-inflammatory action of phenolic compounds from Gastrodia elata root.

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Identifikohuni Regjistrohu
Previous screening of the pharmacological action of Gastrodia elata (GE) root (Orchidaceae) showed that methanol (MeOH) extracts have significant anti-inflammatory properties. The anti-inflammatory agents of GE, however, remain unclear. In this experiment, MeOH extracts of GE were fractionated with

Conjugation of benzylvanillin and benzimidazole structure improves DNA binding with enhanced antileukemic properties.

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Identifikohuni Regjistrohu
Benzyl-o-vanillin and benzimidazole nucleus serve as important pharmacophore in drug discovery. The benzyl vanillin (2-(benzyloxy)-3-methoxybenzaldehyde) compound shows anti-proliferative activity in HL60 leukemia cancer cells and can effect cell cycle progression at G2/M phase. Its apoptosis
Over the past several years, nano-based therapeutics were an effective cancer drug candidate in order to overcome the persistence of deadliest diseases and prevalence of multiple drug resistance (MDR).

Methods
The main objective of our program was to

Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: new achievements.

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Identifikohuni Regjistrohu
In the search for new therapeutic tools against diseases produced by kinetoplastid parasites five vanadyl complexes, [V(IV)O(L-2H)(phen)], including 1,10-phenanthroline (phen) and tridentate salicylaldehyde semicarbazone derivatives as ligands have been synthesized and characterized in the solid
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