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adenine/inflammation

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Faqja 1 nga 27 rezultatet

Use of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Caused by COVID-19

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Identifikohuni Regjistrohu
A Study of Mesenchymal Stem Cells as a treatment in Patients with Acute Respiratory Distress Syndrome caused by COVID-19 is a pilot phase, open label, non-randomized study, with a single study center. The current pandemic caused by the novel virus SARS-CoV-2 has lead to a health care crisis

Effects of Nicotinamide Riboside on the Clinical Outcome of Covid-19 in the Elderly

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Identifikohuni Regjistrohu
Currently the number of SARS-CoV-2 positive patients are increasing worldwide and healthcare systems are attempting to cope with the massive pressure that this pandemic results in. Given the highly infectious virus and the relatively high mortality, this pandemic will likely result in many thousand

Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD)

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Identifikohuni Regjistrohu
Background information Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive fat accumulation in the liver and is defined by evidence of hepatic steatosis (via imaging or histology) and is not due to secondary liver fat accumulation from excessive alcohol consumption or hereditary

Efficacy of Solarplast for Health and Oxidative Stress

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Identifikohuni Regjistrohu
Solarplast is currently sold on the market, which is a unique mixture of antioxidant enzymes and single antioxidant molecules that attack oxidants through chaperone activity. Chaperones, are naturally occurring proteins that assist the non-covalent folding/unfolding and the assembly/disassembly of

Effects of COcoa Supplement in OBese Adolescent Subjects

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Identifikohuni Regjistrohu
Childhood obesity is global health problem, due to the constant increase in its incidence and prevalence. Having this disease helps increase the costs of care for Chronic Noncommunicable Diseases. The increase in its prevalence since 1975 from 1% to 6% (girls) and 8% (boys) in 2016 between the
Background: Risk of cardiovascular diseases (CVD) is significantly elevated in patients with chronic kidney disease (CKD). Arterial dysfunction is an important nontraditional CV risk factor gaining increased recognition in the field of nephrology. While many changes likely contribute to the

Role of Nesfatin-1 and Nicotinamide in Infertile Women With Polycystic Ovary Syndrome

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Identifikohuni Regjistrohu
- Nesfatin-1 is an 82-amino acid polypeptide derived from the nucleobindin 2 (NUCB2) precursor proteins. - It is a newly identified peptide. It is released from several tissues including forebrain, hindbrain, brainstem, spinal cord and adipose tissues. - It plays an important role in hypothalamic

Uric Acid Metabolism, Endothelial Function and Oxidative Stress in Vegans and Omnivores.

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Identifikohuni Regjistrohu
Non-meat eaters rise widely worldwide. This choice answers ideological, ecological or health concerns. Several vegetarian diets exist and the vegan diet is the most restricted one as it excludes all animal products, eggs and dairy. Beside benefits on health and particularly on the cardiovascular

Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults

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Identifikohuni Regjistrohu
Study Overview: This is a randomized, double-blind, placebo-controlled, parallel design, single site phase IIa clinical trial assessing the efficacy of nicotinamide riboside supplementation to lower systolic blood pressure (SBP) and aortic stiffness in middle-aged to older (MA/O) adults (50-79

Nicotinamide Riboside in LVAD Recipients

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Identifikohuni Regjistrohu
This Pilot Study will examine the following Aims: Aim 1: Enroll 5 participants scheduled for elective left ventricular assist device (LVAD) placement into an open-label study of nicotinamide riboside (NR). a. Participants will have labs (including safety panels) drawn at baseline (Day 1), then

Gum Arabic as Antioxidant and Anti-inflammatory in Hemodialysis Patients

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Identifikohuni Regjistrohu
The oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Cells continuously produce free radicals and reactive oxygen species (ROS) as

Mechanisms for Individual Differences in Hypertension in Obstructive Sleep

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Identifikohuni Regjistrohu
We seek to assess the clinical determinants and molecular/genetic mechanisms underlying known individual differences in BP response to obstructive sleep apnea (OSA). This will result in a more personalized approach to BP management of OSA patients. Hypertension is a common consequence of OSA. Animal

Vitamin C in Cardiac Surgery Patients

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Identifikohuni Regjistrohu
The pathophysiology of post-operative atrial fibrillation (POAF) in cardiac surgery patients has not been fully elucidated, but inflammation and oxidative stress are associated with its occurrence. Increased activity of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and production of

Pioglitazone Therapy for Chronic Granulomatous Disease

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Identifikohuni Regjistrohu
Chronic granulomatous disease (CGD) is a rare genetic disease caused by defects in genes encoding the subunits of the nicotinamide adenine dinucleotide(NADPH)phosphate oxidase complex. In normal phagocytes peroxisome proliferator-activated receptor gamma (PPARγ) activation links NADPH oxidase

Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype

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Identifikohuni Regjistrohu
-NAD+ sensitive metabolic decline in ageing, including sarcopenia, leads to a reduction in energy metabolism, contribute to chronic inflammation, disposing individuals to metabolic disease and overall decreased later-life health. Prominent metabolic changes include a decline in NAD+ content and
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