aortic coarctation/kaliumi

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Aortic coarctation: the in vitro response to noradrenaline, potassium and prostaglandin F2 alpha in intercostal arteries.

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Identifikohuni Regjistrohu

Involvement of nitric oxide and potassium channels in the reduction of basal tone produced by blockade of thromboxane A2/prostaglandin H2 receptors in aortic rings of hypertensive rats.

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Identifikohuni Regjistrohu

This study was designed to investigate involvement of potassium channels in the action of nitric oxide facilitating reduction of basal tone by thromboxane A2/prostaglandin H2 receptor blockade with ifetroban in rings of thoracic aorta taken from rats with aortic coarctation-induced hypertension.

Prenatal diagnosis of coarctation of the aorta improves survival and reduces morbidity.

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Identifikohuni Regjistrohu

OBJECTIVE To investigate whether antenatal diagnosis of coarctation of the aorta results in reduced mortality and improved preoperative haemodynamic stability compared with postnatal diagnosis. METHODS Retrospective review of all cases of coarctation of the aorta presenting to a tertiary fetal and

Effects of different stages of aortic coarctation hypertension on aortic contraction and relaxation in rats.

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Identifikohuni Regjistrohu

Contractile responses to norepinephrine, serotonin and potassium (K+) and relaxant responses to isoproterenol and papaverine were studied in vitro with spirally cut thoracic aortic strips from aortic coarcted hypertensive rats (AHR)2, 6, 14 and 28 days postoperatively and compared to time-matched,

Arterial wall metabolism in experimental hypertension of coarctation of the aorta of short duration.

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Coarctation of the mid-thoracic aorata was surgically produced in mongrel dogs which were sacrificed from 4-12 wk after the operation. As compared to the findings in control animals, the sodium, chloride, and water content of the hypetensive portion of the coarcted thoracic aorta was significantly

Effect of celecoxib on the antihypertensive effect of losartan in a rat model of renovascular hypertension.

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Identifikohuni Regjistrohu

Certain nonsteroidal anti-inflammatory drugs have been reported to elevate blood pressure in some hypertensive patients, who are either untreated or treated with antihypertensive agents. This study was undertaken to determine the effect of a selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib,

Vascular responsiveness to nitric oxide synthesis inhibition in hypertensive rats.

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Identifikohuni Regjistrohu

We contrasted in normotensive and hypertensive rats the effect of inhibition of nitric oxide synthesis on isometric tension development by aortic rings bathed in Krebs' bicarbonate buffer. NG-Nitro-L-arginine methyl ester (L-NAME) (3 x 10(-4) mol/L) increased tension (82 +/- 11% of the response to

Prostaglandin E1 treatment in patent ductus arteriosus dependent congenital heart defects.

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Identifikohuni Regjistrohu

Prostaglandin E1 (PGE1) treatment can be life saving in patients suffering from ductus dependent congenital heart defect. We analyzed the indications and side-effects of PGE1 therapy over a five-year period. The purpose of the study was also to examine whether a change in serum electrolyte levels

[Heart surgery in newborn infants and in early infancy].

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Identifikohuni Regjistrohu

During the past five years, 127 newborn infants with marked anoxia, severe cardiac failure or respiratory problems secondary to a cardiac lesion were operated upon at l'Hôpital Ste-Justine, Montreal, Quebec.Infants in cardiorespiratory distress from a cardiac lesion for which the surgical treatment

Inhibition of PKC-dependent extracellular Ca2+ entry contributes to the depression of contractile activity in long-term pressure-overloaded endothelium-denuded rat aortas.

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We examined the contractile responsiveness of rat thoracic aortas under pressure overload after long-term suprarenal abdominal aortic coarctation (lt-Srac). Endothelium-dependent angiotensin II (ANG II) type 2 receptor (AT2R)-mediated depression of contractions to ANG II has been reported in

Effects of calmodulin-dependent protein kinase II inhibitor, KN-93, on electrophysiological features of rabbit hypertrophic cardiac myocytes.

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Cardiac hypertrophy is an independent risk factor for sudden cardiac death in clinical settings and the incidence of sudden cardiac death and ventricular arrhythmias are closely related. The aim of this study was to determine the effects of the calmodulin-dependent protein kinase (CaMK) II

[Role of the changes in the sarcoplasmic reticulum in disorders of myocardial function].

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Identifikohuni Regjistrohu

Acute focal ischemia of the myocardium, acute hemodynamic overloading of the heart, coarctation of the aorta, and fibrillation of the heart were simulated on rabbits. The animals were studied for the contractile function of the myocardium, and potential work capacity of the heart was calculated

Down-regulation of the human ether-a-go-go-related gene in rat cardiac hypertrophy.

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Identifikohuni Regjistrohu

BACKGROUND Cardiac hypertrophy is a risk factor for QT prolongation and cardiac sudden death. In this study, the authors examined the expressional regulation on the rat human ether-a-go-go-related gene (HERG), which encodes a structural subunit of the rapid component of the delayed rectifier

Mineralocorticoid hypertension.

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Identifikohuni Regjistrohu

Hypertension affects about 10 - 25% of the population and is an important risk factor for cardiovascular and renal disease. The renin-angiotensin system is frequently implicated in the pathophysiology of hypertension, be it primary or secondary. The prevalence of primary aldosteronism increases with

Diagnosing secondary hypertension.

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Identifikohuni Regjistrohu

Secondary hypertension is elevated blood pressure that results from an underlying, identifiable, often correctable cause. Only about 5 to 10 percent of hypertension cases are thought to result from secondary causes. The ABCDE mnemonic can be used to help determine a secondary cause of hypertension:

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