gas gangrene/phosphatase

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Genetic and biochemical analysis of a class C non-specific acid phosphatase (NSAP) of Clostridium perfringens.

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Identifikohuni Regjistrohu

Clostridium perfringens, a Gram-positive anaerobe, is a human pathogen that causes gas gangrene in muscle tissues. Its ability to grow and survive in the host is believed to be due to the production of numerous enzymes that enable the organism to obtain essential nutrients from the host. In this

Histochemical and electron microscopical studies of skeletal muscle affected by gas gangrene.

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Identifikohuni Regjistrohu

Ultrastructural and histochemical changes of skeletal muscle were studied in three patients affected with gas gangrene. There was complete lack of the phosphorylase, succinate dehydrogenase and adenosine triphosphatase activities in the affected muscles of all the patients. In unaffected muscles

Effects of photobiomodulation therapy on Bothrops moojeni snake-envenomed gastrocnemius of mice using enzymatic biomarkers.

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Identifikohuni Regjistrohu

Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein,

Role of nitric oxide in myotoxic activity induced by crotoxin in vivo.

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Identifikohuni Regjistrohu

This study was aimed to determine the role of nitric oxide on the skeletal myotoxic activity induced by crotoxin, the major component of the venom of Crotalus durissus terrificus. Rats were treated with N(G)-nitro-L-arginine methyl ester (L-NAME), a non-selective inhibitor of nitric oxide synthase

Cyclosporin A attenuates skeletal muscle damage induced by crotoxin in rats.

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Identifikohuni Regjistrohu

This work was undertaken to determine the role of the calcineurin pathway on the necrosis of skeletal muscle induced by crotoxin, the major component of the venom of Crotalus durissus terrificus. Rats were treated with cyclosporin A (CsA), a calcineurin inhibitor, for 5 days and, in the 6th day,

Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mice.

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Identifikohuni Regjistrohu

The local and systemic pathological changes induced by an i.m. injection of 100 micrograms of Bothrops asper venom in mice were studied histologically and by following the changes in serum levels of enzymes, proteins, ATP and lactate, as well as alterations in hematocrit and clotting time. B. asper

Palatal myositis in horses with dorsal displacement of the soft palate.

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Identifikohuni Regjistrohu

The histologic and histochemical features of palatine muscles from 53 horses were studied; 25 of the horses were racehorses that had upper airway obstruction associated with dorsal displacement of the soft palate and 28 of the horses did not have any respiratory disorders and served as controls.

Facioscapulohumeral muscular dystrophy: muscle fiber type analysis with particular reference to small angular fibers.

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Identifikohuni Regjistrohu

Muscle biopsies from 14 patients with facioscapulohumeral muscular dystrophy (FSHD) aged from 5 to 45 years were studied histochemically with fiber type analysis, focusing on small angular fibers (SAF) to clarify their significance. There were no duration-related or age-dependent histopathological

Lipin-1 regulates autophagy clearance and intersects with statin drug effects in skeletal muscle.

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Identifikohuni Regjistrohu

LPIN1 encodes lipin-1, a phosphatidic acid phosphatase (PAP) enzyme that catalyzes the dephosphorylation of phosphatidic acid to form diacylglycerol. Homozygous LPIN1 gene mutations cause severe rhabdomyolysis, and heterozygous LPIN1 missense mutations may promote statin-induced myopathy. We

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