4 rezultatet
BACKGROUND
Gouania longipetala Hemsl. (Rhamnaceae) is used in folkloric medicine for treating diabetes mellitus and its associated symptoms.
OBJECTIVE
This study evaluated the antidiabetic antilipidemic and antioxidant activities of the plant methanol leaf extract.
METHODS
Diabetes was induced in
BACKGROUND
Adipose cells responsible for fat storage are the targets of reactive oxygen species (ROS) like H2O2 and pro-inflammatory agents including TNFα and LPS. Such mediators contribute to oxidative stress and alter inflammatory processes in adipose tissue, leading to insulin resistance during
3-O-β-D-glucopyranosyl gouanogenin A (1), a new naturally occurring dammarane class of triterpene glucoside, has been isolated from the aerial parts of Gouania longipetala along with six known secondary metabolites 2-7. Their structure was elucidated through spectroscopic
BACKGROUND
Gouania longipetala leaves are commonly used in folkloric medicine in Africa and other parts of the world for treatment of edema, febrifuges, veneral diseases, lumbago, heart diseases, diabetes mellitus malaria, etc. This study therefore evaluated safety profile of the methanol leaf