hepatic veno-occlusive disease/phosphatase

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Gemtuzumab ozogamicin (MylotargTM) is infrequently associated with sinusoidal obstructive syndrome/veno-occlusive disease.

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Identifikohuni Regjistrohu

BACKGROUND Gemtuzumab ozogamicin (GO) is approved for the treatment of older adults with acute myeloid leukemia in first relapse. Several reports have suggested an association between GO administration and hepatic veno-occlusive disease (VOD), which has recently been termed sinusoidal obstructive

Intravenous immunoglobulin and the risk of hepatic veno-occlusive disease after bone marrow transplantation.

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Identifikohuni Regjistrohu

Recent reports using historical controls or registry cohorts suggest, respectively, either an increase in the mortality or a decrease in the incidence of hepatic veno-occlusive disease (VOD) with the administration of intravenous immunoglobulin (i.v.Ig) after bone marrow transplantation. These

[Hepatic veno-occlusive disease associated to the use of azathioprine in a renal transplant recipient].

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Identifikohuni Regjistrohu

We report a 30 years old male, recipient of a kidney allograft and treated with azathioprine, who eighteen days after transplantation had a clinically asymptomatic elevation of total bilirubin and alkaline phosphatases. Nineteen months later, he presented with mild ascites, with a total bilirubin of

Bile duct adenocarcinoma mimicking veno-occlusive disease after autologous bone marrow transplantation for acute leukaemia.

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A 52-year-old female underwent autologous BMT because of acute myeloid leukaemia FAB M4 in second remission. Since the patient had no HLA-identical sibling she received a purged autologous BM transplant. On day +5 she developed signs of a sepsis syndrome with fluid retention and was treated with

Liver pathology following hepatic arterial infusion chemotherapy. Hepatic toxicity with FUDR.

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Identifikohuni Regjistrohu

The authors reviewed the liver histopathology and the clinical features of eight patients with liver metastases from colorectal cancer who were treated by hepatic arterial infusion chemotherapy (HAIC) via an implantable pump (Infusaid). Before HAIC, these patients had no evidence of hepatitis, and

Hepatic arterial resistance index--an indicator of diffuse liver disease in children treated with bone marrow transplantation.

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Identifikohuni Regjistrohu

OBJECTIVE To describe the relationship between the resistance index of the common hepatic artery and liver function tests in children undergoing bone marrow transplantation. METHODS We analysed prospectively the results of 106 Doppler ultrasound examinations of the common hepatic artery from 31 bone

Long non-coding RNAs expression profiles in hepatocytes of mice after hematopoietic stem cell transplantation.

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Identifikohuni Regjistrohu

Hepatic veno-occlusive disease (HVOD), one serious complication following hematopoietic stem cell transplantation (HSCT), is mainly initiated by the damage to sinusoidal endothelial cells and hepatocytes. Long non-coding RNAs (lncRNAs) play an important role in the proliferation of hepatocytes and

Liver disease is a major cause of mortality following allogeneic bone-marrow transplantation.

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Identifikohuni Regjistrohu

BACKGROUND Liver disease is an important cause of morbidity and mortality among recipients of bone-marrow transplantation (BMT). The aim of this retrospective study was to determine the incidence, risk factors and clinical evolution of liver disease following allogeneic BMT. METHODS A total of 103

Hepatic dysfunction following busulfan and cyclophosphamide myeloablation: a retrospective, multicenter analysis.

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Identifikohuni Regjistrohu

Veno-occlusive disease continues to be a significant cause of morbidity and early mortality following bone marrow transplantation. This study retrospectively analyzes the incidence and risk factors for severe VOD in 350 patients treated with 4 days of busulfan (total 16 mg/kg) and 2 days of

A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury.

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Identifikohuni Regjistrohu

BACKGROUND Human liver has an unusual sensitivity to radiation that limits its use in cancer therapy or in preconditioning for hepatocyte transplantation. Because the characteristic veno-occlusive lesions of radiation-induced liver disease do not occur in rodents, there has been no experimental

Histologic changes mimicking biliary disease in liver biopsies with venous outflow impairment.

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Identifikohuni Regjistrohu

Impairment of venous outflow from the liver manifests as zone 3 sinusoidal dilatation and congestion (SDC) in liver biopsy. The spectrum of histologic changes in portal tracts has not been described. We studied liver biopsies from 34 patients with a confirmed diagnosis of venous outflow impairment

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